staurosporine


SMILES CN[C@@H]1C[C@H]2O[C@]([C@@H]1OC)(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O
InChIKey HKSZLNNOFSGOKW-FYTWVXJKSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 2
Molecular weight (Da) 466.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug Yes

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
A2B AA2BR Human Adenosine A pKi 5.7 6.0 6.3 Guide to Pharmacology
A2B AA2BR Human Adenosine A pKi 8.42 8.42 8.42 ChEMBL
A1 AA1R Rat Adenosine A pKi 5.28 5.28 5.28 PDSP Ki database
A2A AA2AR Human Adenosine A pKi 6.03 6.03 6.03 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database