zinterol


SMILES OC(c1ccc(c(c1)NS(=O)(=O)C)O)CNC(Cc1ccccc1)(C)C
InChIKey XJBCFFLVLOPYBV-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 4
Rotatable bonds 8
Molecular weight (Da) 378.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
SST1 SSR1 Human Somatostatin A pKd 8.0 8.05 8.1 Guide to Pharmacology
SST2 SSR2 Rat Somatostatin A pKd 5.11 5.11 5.11 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKd 6.95 6.95 6.95 ChEMBL
D4 DRD4 Human Dopamine A pKd 8.3 8.3 8.3 ChEMBL
β1 ADRB1 Human Adrenoceptors A pKd 6.65 6.65 6.65 ChEMBL
SST1 SSR1 Human Somatostatin A pKd 7.99 7.99 7.99 ChEMBL
SST2 SSR2 Human Somatostatin A pKd 4.44 4.44 4.44 ChEMBL
SST3 SSR3 Human Somatostatin A pKd 5.06 5.06 5.06 ChEMBL
SST4 SSR4 Human Somatostatin A pKd 4.82 4.82 4.82 ChEMBL
SST5 SSR5 Human Somatostatin A pKd 5.75 5.75 5.75 ChEMBL
SST1 SSR1 Rat Somatostatin A pKd 9.15 9.15 9.15 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database