vincamine


SMILES COC(=O)[C@@]1(O)C[C@]2(CC)CCCN3[C@@H]2c2n1c1ccccc1c2CC3
InChIKey RXPRRQLKFXBCSJ-GIVPXCGWSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 2
Molecular weight (Da) 354.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug Yes

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pKi 8.1 8.1 8.1 Drug Central
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 8.12 8.12 8.12 Drug Central
5-HT1F 5HT1F Human 5-Hydroxytryptamine A pKi 8.14 8.14 8.14 Drug Central
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pIC50 7.89 7.89 7.89 Guide to Pharmacology
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pIC50 7.92 7.92 7.92 Guide to Pharmacology