RP67580


SMILES COc1ccccc1CC(=N)N1C[C@H]2[C@@H](C1)C(CCC2=O)(c1ccccc1)c1ccccc1
InChIKey VWBOQFANCXZMAU-LOSJGSFVSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 438.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
EP2 PE2R2 Human Prostanoid A pKi 8.28 8.28 8.28 Drug Central
EP4 PE2R4 Human Prostanoid A pKi 8.27 8.27 8.27 Drug Central
IP PI2R Human Prostanoid A pKi 8.11 8.11 8.11 Drug Central
IP PI2R Human Prostanoid A pKi 6.59 6.59 6.59 Guide to Pharmacology
IP PI2R Rat Prostanoid A pKi 8.25 8.25 8.25 Drug Central
IP PI2R Rat Prostanoid A pKi 5.68 5.68 5.68 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
DP1 PD2R Human Prostanoid A pEC50 8.15 8.15 8.15 Drug Central
DP1 PD2R Human Prostanoid A pEC50 7.0 7.0 7.0 ChEMBL
IP PI2R Human Prostanoid A pEC50 8.22 8.22 8.22 ChEMBL
IP PI2R Human Prostanoid A pIC50 7.21 7.21 7.21 ChEMBL
IP PI2R Rat Prostanoid A pEC50 6.7 6.7 6.7 ChEMBL