R-PSOP


SMILES O=C(Nc1ccccc1)Nc1cnc2c(c1)C[C@]1(O2)CN2CC[C@H]1CC2
InChIKey BUOWEYLLAFLKCW-FQEVSTJZSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 2
Molecular weight (Da) 350.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
GLP-1 GLP1R Human Glucagon B1 pKd 6.36 6.36 6.36 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
GLP-1 GLP1R Human Glucagon B1 pIC50 7.52 8.71 9.89 ChEMBL
GLP-1 GLP1R Human Glucagon B1 pEC50 10.73 10.73 10.73 ChEMBL
GLP-1 GLP1R Human Glucagon B1 pIC50 8.03 8.03 8.03 Drug Central
GLP-1 GLP1R Human Glucagon B1 pEC50 11.21 11.21 11.21 Guide to Pharmacology
GLP-1 GLP1R Human Glucagon B1 pIC50 9.42 9.42 9.42 Guide to Pharmacology