SB328437


SMILES COC(=O)[C@@H](NC(=O)c1ccc2c(c1)cccc2)Cc1ccc(cc1)N(=O)=O
InChIKey KOLBWAVLYDRUOC-IBGZPJMESA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 378.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NK3 NK3R Human Tachykinin A pKi 8.62 8.62 8.62 ChEMBL
NK2 NK2R Human Tachykinin A pKi 8.62 8.62 8.62 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NK3 NK3R Human Tachykinin A pIC50 5.62 5.62 5.62 ChEMBL
NK1 NK1R Human Tachykinin A pIC50 8.02 9.12 10.22 ChEMBL
NK1 NK1R Human Tachykinin A pIC50 10.22 10.22 10.22 Guide to Pharmacology
NK2 NK2R Human Tachykinin A pIC50 5.62 5.62 5.62 ChEMBL