UCB35625


SMILES CC[N+]1(CCC(CC1)NC(=O)C1c2cc(Cl)ccc2Oc2c1cc(Cl)cc2)CC1CCCCCC1
InChIKey ZTXGBIXSMSZDOC-UHFFFAOYSA-O

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 515.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC1 MSHR Human Melanocortin A pKi 8.34 8.34 8.34 ChEMBL
MC3 MC3R Human Melanocortin A pKi 7.88 7.88 7.88 ChEMBL
MC4 MC4R Human Melanocortin A pKi 8.37 8.38 8.39 ChEMBL
MC1 MSHR Human Melanocortin A pKi 8.08 8.08 8.08 Drug Central
MC1 MSHR Human Melanocortin A pKi 8.41 8.41 8.41 Guide to Pharmacology
MC3 MC3R Human Melanocortin A pKi 8.1 8.1 8.1 Drug Central
MC3 MC3R Human Melanocortin A pKi 8.0 8.0 8.0 Guide to Pharmacology
MC4 MC4R Human Melanocortin A pKd 8.06 8.06 8.06 Drug Central
MC4 MC4R Human Melanocortin A pKi 8.68 8.68 8.68 Guide to Pharmacology
MC5 MC5R Human Melanocortin A pKi 8.2 8.2 8.2 Drug Central
MC5 MC5R Human Melanocortin A pKi 6.37 6.37 6.37 Guide to Pharmacology
MC4 MC4R Rat Melanocortin A pKi 8.57 8.57 8.57 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC1 MSHR Human Melanocortin A pEC50 9.8 9.8 9.8 ChEMBL
MC5 MC5R Human Melanocortin A pIC50 5.72 5.72 5.73 ChEMBL
MC3 MC3R Human Melanocortin A pEC50 9.82 9.82 9.82 ChEMBL
MC4 MC4R Human Melanocortin A pEC50 9.4 9.41 9.41 ChEMBL