urocortin 2


SMILES None
InChIKey None
Sequence VILSLDVPIGLLRILLEQARNKAARNQAATNAQILARV

Chemical properties

Hydrogen bond acceptors None
Hydrogen bond donors None
Rotatable bonds None
Molecular weight (Da)

Drug properties

Molecular type Peptide
Endogenous/Surrogate Endogenous
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu5 GRM5 Human Metabotropic glutamate C pKi 6.54 6.54 6.54 ChEMBL
mGlu4 GRM4 Human Metabotropic glutamate C pKi 4.58 4.58 4.58 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu5 GRM5 Rat Metabotropic glutamate C pIC50 5.97 5.97 5.97 ChEMBL
mGlu5 GRM5 Human Metabotropic glutamate C pIC50 5.52 6.01 6.54 ChEMBL
NPS NPSR1 Human Neuropeptide S A Potency 5.0 5.0 5.0 ChEMBL
mGlu4 GRM4 Human Metabotropic glutamate C pEC50 6.3 6.55 6.8 Guide to Pharmacology
mGlu5 GRM5 Human Metabotropic glutamate C pIC50 5.9 6.2 6.5 Guide to Pharmacology