W-84


SMILES O=C1N(CCC[N+](CCCCCC[N+](CCCN2C(=O)c3c(C2=O)cccc3)(C)C)(C)C)C(=O)c2c1cccc2
InChIKey WDAXQFXYXWPELC-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 15
Molecular weight (Da) 548.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu7 GRM7 Human Metabotropic glutamate C pKi 4.4 4.4 4.4 Guide to Pharmacology
mGlu2 GRM2 Rat Metabotropic glutamate C pKi 5.3 5.3 5.3 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu6 GRM6 Rat Metabotropic glutamate C pEC50 4.1 4.1 4.1 Guide to Pharmacology
mGlu8 GRM8 Rat Metabotropic glutamate C pIC50 5.3 5.3 5.3 Guide to Pharmacology