compound 2b-1 [PMID: 12614873]


SMILES NC[C@@H]1CCCN(C1)C(=O)c1ccc2c(c1)C(C(=O)NC1CCN(CC1)CC1=CCCCCCCC1)c1c(O2)cccc1
InChIKey AAPRNHKWNGDTOT-DVRVPOOOSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 6
Molecular weight (Da) 584.4

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
EP2 PE2R2 Human Prostanoid A pKi 8.0 8.0 8.0 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
EP2 PE2R2 Human Prostanoid A pEC50 8.55 8.55 8.55 ChEMBL
EP2 PE2R2 Human Prostanoid A pIC50 8.0 8.0 8.0 Guide to Pharmacology
EP2 PE2R2 Rat Prostanoid A pIC50 8.3 8.3 8.3 Guide to Pharmacology