resolvin D1


SMILES CC/C=C\C[C@@H](/C=C/C=C\C=C\C=C\[C@@H]([C@H](C/C=C\CCC(=O)O)O)O)O
InChIKey OIWTWACQMDFHJG-LDOXQWQISA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 4
Rotatable bonds 14
Molecular weight (Da) 376.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Endogenous
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
SMO SMO Human Frizzled F pKi 7.79 7.85 7.91 ChEMBL
SMO SMO Human Frizzled F pKd 7.01 7.01 7.01 ChEMBL
SMO SMO Human Frizzled F pKi 8.11 8.11 8.11 Drug Central
SMO SMO Human Frizzled F pKi 7.79 7.79 7.79 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
SMO SMO Mouse Frizzled F pIC50 6.4 7.7 8.82 ChEMBL
SMO SMO Mouse Frizzled F pEC50 8.33 8.52 8.7 ChEMBL
SMO SMO Human Frizzled F pIC50 7.13 8.0 9.4 ChEMBL
SMO SMO Human Frizzled F pEC50 8.52 8.61 8.7 ChEMBL
SMO SMO Mouse Frizzled F pIC50 8.08 8.08 8.08 Drug Central