DAX


SMILES C=CCn1c2nc([nH]c2c(=O)n(c1=O)CC=C)C1CCCCC1
InChIKey JPIQZRAYPNKFEI-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 314.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NK1 NK1R Human Tachykinin A pKi 10.05 10.05 10.05 Guide to Pharmacology
NK1 NK1R Human Tachykinin A pKi 7.97 7.97 7.97 Drug Central
NK3 NK3R Human Tachykinin A pKi 8.2 8.2 8.2 Drug Central
NK1 NK1R Human Tachykinin A pKi 8.52 9.24 10.1 ChEMBL
NK1 NK1R Human Tachykinin A pKd 8.08 8.08 8.08 ChEMBL
NK3 NK3R Human Tachykinin A pKi 6.34 6.34 6.34 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NK1 NK1R Mongolian jird Tachykinin A pIC50 8.0 8.0 8.0 Drug Central
NK1 NK1R Human Tachykinin A pIC50 8.85 9.92 10.05 ChEMBL
NK1 NK1R Mongolian jird Tachykinin A pIC50 10.05 10.05 10.05 ChEMBL