OSIP339391


SMILES CC(=O)NCCNc1nc(nc2c1cc([nH]2)C(=O)N1CCN(CC1)CCCc1ccccc1)c1ccccc1
InChIKey MIUCZFWBCFZKEU-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 3
Rotatable bonds 10
Molecular weight (Da) 525.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CB1 CNR1 Rat Cannabinoid A pKi 8.9 8.9 8.9 Guide to Pharmacology
CB1 CNR1 Rat Cannabinoid A pKi 5.47 7.53 8.85 ChEMBL
CB2 CNR2 Human Cannabinoid A pKi 7.02 7.02 7.02 ChEMBL
CB1 CNR1 Human Cannabinoid A pKi 8.28 8.28 8.28 ChEMBL
CB1 CNR1 Mouse Cannabinoid A pKi 8.41 8.41 8.41 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CB1 CNR1 Rat Cannabinoid A pEC50 6.5 6.5 6.5 ChEMBL