MPC-MECA


SMILES CCNC(=O)[C@H]1O[C@H]([C@@H]([C@@H]1O)O)n1cnc2c1ncnc2NCc1ccc(cc1)OC
InChIKey BNXGNSTUSRFBCI-KSVNGYGVSA-N

Chemical properties

Hydrogen bond acceptors 10
Hydrogen bond donors 4
Rotatable bonds 7
Molecular weight (Da) 428.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M1 ACM1 Human Acetylcholine (muscarinic) A pKi 6.4 6.4 6.4 Guide to Pharmacology
M2 ACM2 Human Acetylcholine (muscarinic) A pKi 5.7 5.7 5.7 Guide to Pharmacology
M3 ACM3 Human Acetylcholine (muscarinic) A pKi 5.7 5.7 5.7 Guide to Pharmacology
M4 ACM4 Human Acetylcholine (muscarinic) A pKi 5.9 5.9 5.9 Guide to Pharmacology
M4 ACM4 Human Acetylcholine (muscarinic) A pKi 6.01 6.01 6.01 ChEMBL
M1 ACM1 Human Acetylcholine (muscarinic) A pKi 5.91 5.91 5.91 ChEMBL
M2 ACM2 Human Acetylcholine (muscarinic) A pKi 7.06 7.06 7.06 ChEMBL
M3 ACM3 Human Acetylcholine (muscarinic) A pKi 6.07 6.07 6.07 ChEMBL
M5 ACM5 Human Acetylcholine (muscarinic) A pKi 6.03 6.03 6.03 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database