cirazoline


SMILES C1CN=C(N1)COc1ccccc1C1CC1
InChIKey YAORIDZYZDUZCM-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 216.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug Yes

Database connections

Ligand site mutations α1A α1B

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu8 GRM8 Human Metabotropic glutamate C pKB 5.43 5.43 5.43 Guide to Pharmacology
mGlu8 GRM8 Human Metabotropic glutamate C pEC50 6.0 6.0 6.0 Guide to Pharmacology
mGlu5 GRM5 Rat Metabotropic glutamate C pKB 5.38 5.38 5.38 Guide to Pharmacology