guanfacine


SMILES O=C(Cc1c(Cl)cccc1Cl)N=C(N)N
InChIKey INJOMKTZOLKMBF-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 1
Hydrogen bond donors 2
Rotatable bonds 2
Molecular weight (Da) 245.0

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug Yes

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
DP2 PD2R2 Human Prostanoid A pIC50 8.37 8.37 8.37 Guide to Pharmacology
DP2 PD2R2 Human Prostanoid A pIC50 8.0 8.25 8.37 ChEMBL