carvedilol


SMILES COc1ccccc1OCCNCC(COc1cccc2c1c1ccccc1[nH]2)O
InChIKey OGHNVEJMJSYVRP-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 3
Rotatable bonds 10
Molecular weight (Da) 406.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug Yes

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CCR3 CCR3 Human Chemokine A pKi 8.5 8.5 8.5 Guide to Pharmacology
CCR3 CCR3 Human Chemokine A pKd 8.3 8.3 8.3 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CCR3 CCR3 Human Chemokine A pIC50 8.64 8.64 8.64 ChEMBL
CCR1 CCR1 Human Chemokine A pIC50 5.72 5.72 5.72 ChEMBL