amibegron


SMILES CCOC(=O)COc1ccc2c(c1)C[C@H](CC2)NC[C@@H](c1cccc(c1)Cl)O
InChIKey RDJQCOBTKKAQAH-FPOVZHCZSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 8
Molecular weight (Da) 403.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug Yes

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CCR3 CCR3 Human Chemokine A pKi 8.5 8.5 8.5 Guide to Pharmacology
CCR3 CCR3 Human Chemokine A pKd 8.3 8.3 8.3 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CCR1 CCR1 Human Chemokine A pIC50 5.72 5.72 5.72 ChEMBL
CCR3 CCR3 Human Chemokine A pIC50 8.64 8.64 8.64 ChEMBL