compound 2g [PMID: 19309152]


SMILES O=C(Nc1ccccc1C(=O)O)CCc1cnn2c1CCc1c2ccc(c1)O
InChIKey PCUNTWOSLIUDRR-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 3
Rotatable bonds 5
Molecular weight (Da) 377.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pKi 9.22 9.22 9.22 ChEMBL
μ OPRM Human Opioid A pKi 8.66 8.66 8.66 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pIC50 8.28 8.28 8.28 ChEMBL