AMG7703


SMILES CC([C@H](C(=O)Nc1nccs1)c1ccc(cc1)Cl)C
InChIKey AZYDQCGCBQYFSE-LBPRGKRZSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 294.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pKi 7.51 7.51 7.51 ChEMBL
μ OPRM Human Opioid A pKi 7.52 7.52 7.52 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pIC50 7.23 7.23 7.23 ChEMBL