AMG7703


SMILES CC([C@H](C(=O)Nc1nccs1)c1ccc(cc1)Cl)C
InChIKey AZYDQCGCBQYFSE-LBPRGKRZSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 294.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Human Dopamine A pKi 6.3 7.53 8.2 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.3 6.4 6.5 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database