AMG7703


SMILES CC([C@H](C(=O)Nc1nccs1)c1ccc(cc1)Cl)C
InChIKey AZYDQCGCBQYFSE-LBPRGKRZSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 294.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H3 HRH3 Rat Histamine A pKi 7.72 7.72 7.72 ChEMBL
H3 HRH3 Human Histamine A pKi 7.72 7.72 7.72 ChEMBL
H4 HRH4 Human Histamine A pKi 6.37 6.37 6.37 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database