FR181157


SMILES OC(=O)COc1cccc(c1)CC1CCCC=C1c1nc(c(o1)c1ccccc1)c1ccccc1
InChIKey QVZSFHJAGXKMMQ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 8
Molecular weight (Da) 465.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H3 HRH3 Rat Histamine A pKi 7.7 7.73 7.75 ChEMBL
H3 HRH3 Human Histamine A pKi 7.04 7.04 7.04 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database