lorazepam
SMILES | Clc1ccc2c(c1)C(=NC(C(=O)N2)O)c1ccccc1Cl |
InChIKey | DIWRORZWFLOCLC-UHFFFAOYSA-N |
Chemical properties
Hydrogen bond acceptors | 3 |
Hydrogen bond donors | 2 |
Rotatable bonds | 1 |
Molecular weight (Da) | 320.0 |
Drug properties
Molecular type | Small molecule |
Endogenous/Surrogate | Surrogate |
Approved drug | Yes |
Database connections
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
H3 | HRH3 | Rat | Histamine | A | pKi | 7.64 | 7.64 | 7.64 | ChEMBL |
H4 | HRH4 | Human | Histamine | A | pKi | 6.2 | 6.2 | 6.2 | ChEMBL |
H3 | HRH3 | Human | Histamine | A | pKi | 7.39 | 7.39 | 7.39 | ChEMBL |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |