VU0092145


SMILES Cc1ccc(cc1)N1C(Nc2c(C1=O)cccc2)C(c1ccccc1)C
InChIKey QZAOSZVJAXUJFE-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 3
Molecular weight (Da) 342.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
A2B AA2BR Human Adenosine A pKi 9.0 9.0 9.0 ChEMBL
A3 AA3R Human Adenosine A pKi 5.87 5.87 5.87 ChEMBL
A2A AA2AR Human Adenosine A pKi 7.52 7.52 7.52 ChEMBL
A1 AA1R Human Adenosine A pKi 7.09 7.09 7.09 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database