compound 10 [PMID: 15482906]


SMILES Fc1cc(Oc2cccnc2)cc(c1)n1nnc(n1)c1ccccn1
InChIKey IQSMPFFGKFZZMI-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 334.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKi 8.22 8.22 8.22 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.72 6.72 6.72 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database