NVP-SAA164


SMILES CN1CCN(CC1)C(=O)C1CCN(CC1)S(=O)(=O)c1ccc(c(c1)C(=O)N1CCOCC1)NCC(c1ccccc1)c1ccccc1
InChIKey VODUCDWVPSEMSZ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 1
Rotatable bonds 9
Molecular weight (Da) 659.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D2 DRD2 Human Dopamine A pKi 9.85 9.85 9.85 Guide to Pharmacology
D1 DRD1 Rat Dopamine A pKi 5.54 5.54 5.54 PDSP Ki database
D2 DRD2 Rat Dopamine A pKi 7.83 7.83 7.83 PDSP Ki database
H1 HRH1 Rat Histamine A pKi 5.52 5.52 5.52 PDSP Ki database
β2 ADRB2 Rat Adrenoceptors A pKi 5.0 5.0 5.0 PDSP Ki database
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 8.04 8.04 8.04 Drug Central
α1A ADA1A Human Adrenoceptors A pKi 8.14 8.14 8.14 Drug Central
D2 DRD2 Human Dopamine A pKi 8.01 8.01 8.01 Drug Central
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 9.09 9.09 9.09 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 9.09 9.09 9.09 Guide to Pharmacology
D2 DRD2 Human Dopamine A pKi 9.85 9.85 9.85 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database