8-OH-DPAT


SMILES CCCN(C1CCc2c(C1)c(O)ccc2)CCC
InChIKey ASXGJMSKWNBENU-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 247.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Ligand site mutations 5-HT1A 5-HT1B 5-HT2C

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
EP3 PE2R3 Rat Prostanoid A pKi 8.5 8.5 8.5 Guide to Pharmacology
EP3 PE2R3 Mouse Prostanoid A pKi 8.82 8.82 8.82 Guide to Pharmacology
EP2 PE2R2 Rat Prostanoid A pKi 7.5 7.5 7.5 Guide to Pharmacology
EP4 PE2R4 Mouse Prostanoid A pKi 7.6 7.6 7.6 Guide to Pharmacology
EP2 PE2R2 Mouse Prostanoid A pKi 7.3 7.3 7.3 Guide to Pharmacology
EP4 PE2R4 Human Prostanoid A pKi 8.9 8.9 8.9 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
EP4 PE2R4 Human Prostanoid A pEC50 9.33 9.33 9.33 Guide to Pharmacology