benzquinamide


SMILES CCN(C(=O)C1CN2CCc3c(C2CC1OC(=O)C)cc(c(c3)OC)OC)CC
InChIKey JSZILQVIPPROJI-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 404.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug Yes

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 5.8 5.8 5.8 ChEMBL
α1B ADA1B Human Adrenoceptors A pKi 6.5 6.5 6.5 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.1 7.1 7.1 ChEMBL
D3 DRD3 Human Dopamine A pKi 8.4 8.4 8.4 ChEMBL
H1 HRH1 Human Histamine A pKi 5.7 5.7 5.7 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pEC50 6.1 6.1 6.1 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pEC50 6.3 6.3 6.3 ChEMBL
D2 DRD2 Human Dopamine A pEC50 9.2 9.2 9.2 ChEMBL