compound 17 [PMID: 15300839]


SMILES COc1ccc(cc1)S(=O)(=O)N[C@@H]1CCCC[C@H]1NC(c1cccc2c1cccc2)C
InChIKey AKPJKVQQBSNRID-XTEKXTAFSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 7
Molecular weight (Da) 438.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
DP1 PD2R Human Prostanoid A pKi 8.4 8.9 9.4 Guide to Pharmacology
DP1 PD2R Rat Prostanoid A pKi 7.8 7.8 7.8 Guide to Pharmacology
DP1 PD2R Mouse Prostanoid A pKi 6.6 6.6 6.6 Guide to Pharmacology
FP PF2R Mouse Prostanoid A pKi 5.77 5.77 5.77 PDSP Ki database
DP1 PD2R Mouse Prostanoid A pKi 6.6 6.6 6.6 PDSP Ki database
EP1 PE2R1 Human Prostanoid A pKi 5.0 5.0 5.0 PDSP Ki database
EP4 PE2R4 Human Prostanoid A pKi 6.66 6.77 6.88 PDSP Ki database
DP1 PD2R Human Prostanoid A pKi 9.4 9.4 9.4 PDSP Ki database
EP3 PE2R3 Human Prostanoid A pKi 5.0 5.0 5.0 PDSP Ki database
FP PF2R Human Prostanoid A pKi 5.0 5.0 5.0 PDSP Ki database
IP PI2R Human Prostanoid A pKi 5.0 5.0 5.0 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database