JNJ-16567083


SMILES CO[C@@H]1CC[C@@H](CC1)C(=O)c1ccc2c(c1)cc(c(n2)C)CC
InChIKey VEURHZYLLRSEGL-RHNCMZPLSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 311.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D5 DRD5 Human Dopamine A pKi 7.99 7.99 7.99 ChEMBL
D1 DRD1 Human Dopamine A pKi 7.54 7.54 7.54 ChEMBL
D4 DRD4 Human Dopamine A pKi 6.65 6.65 6.65 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.29 6.29 6.29 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.26 7.26 7.26 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database