JWH-133


SMILES CCCC(c1ccc2c(c1)OC([C@H]1[C@H]2CC(=CC1)C)(C)C)(C)C
InChIKey YSBFLLZNALVODA-RBUKOAKNSA-N

Chemical properties

Hydrogen bond acceptors 1
Hydrogen bond donors 0
Rotatable bonds 3
Molecular weight (Da) 312.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CCR1 CCR1 Human Chemokine A pKi 9.0 9.0 9.0 ChEMBL
CCR1 CCR1 Human Chemokine A pKd 9.0 9.0 9.0 ChEMBL
CCR1 CCR1 Human Chemokine A pKi 8.2 8.6 9.0 Guide to Pharmacology
CCR1 CCR1 Mouse Chemokine A pKd 6.7 6.7 6.7 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CCR1 CCR1 Human Chemokine A pIC50 6.26 8.15 9.4 ChEMBL
CCR1 CCR1 Mouse Chemokine A pIC50 5.82 6.02 6.21 ChEMBL
CCR1 Q9JLY8 Rat Chemokine A pIC50 7.23 7.23 7.23 ChEMBL