pipotiazine


SMILES OCCC1CCN(CC1)CCCN1c2ccccc2Sc2c1cc(cc2)S(=O)(=O)N(C)C
InChIKey JOMHSQGEWSNUKU-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 8
Molecular weight (Da) 475.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug Yes

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CB2 CNR2 Human Cannabinoid A pKi 6.2 6.2 6.2 ChEMBL
CB1 CNR1 Human Cannabinoid A pKd 8.8 8.8 8.8 ChEMBL
CB1 CNR1 Human Cannabinoid A pKi 8.52 8.52 8.52 ChEMBL
CB1 CNR1 Human Cannabinoid A pKi 8.52 8.52 8.52 PDSP Ki database
CB2 CNR2 Human Cannabinoid A pKi 6.2 6.2 6.2 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database