compound 1a [PMID: 24900311]


SMILES COc1cc(OC)cc(c1)C(=O)NNC(=O)Nc1ccc2c(c1)cccc2
InChIKey IFQNPGNCFXITTG-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 3
Rotatable bonds 4
Molecular weight (Da) 365.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pKi 7.47 7.47 7.47 ChEMBL
δ OPRD Human Opioid A pKi 5.22 5.22 5.22 ChEMBL
κ OPRK Human Opioid A pKi 5.52 5.52 5.52 ChEMBL
μ OPRM Human Opioid A pKi 5.71 5.71 5.71 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database