YM-355179


SMILES O=C(C=C1CCN(CC1)C(=O)c1ncc(cc1O)C)N[C@@H]1CCN(C1)Cc1ccc2c(c1)ccc(c2)F
InChIKey LHTPHICFHRATTG-RUZDIDTESA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 5
Molecular weight (Da) 502.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CaS CASR Mouse Calcium-sensing C pKd 2.5 2.5 2.5 Guide to Pharmacology
CaS CASR Rat Calcium-sensing C pKd 2.5 2.5 2.5 Guide to Pharmacology
CaS CASR Human Calcium-sensing C pKd 2.4 2.4 2.4 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database