EMD-386088


SMILES Clc1ccc2c(c1)c(C1=CCNCC1)c([nH]2)C
InChIKey BPPGPYJBCVXILI-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 1
Hydrogen bond donors 2
Rotatable bonds 1
Molecular weight (Da) 246.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT6 5HT6R Human 5-Hydroxytryptamine A pIC50 8.13 8.13 8.13 Guide to Pharmacology
5-HT1B 5HT1B Rat 5-Hydroxytryptamine A pIC50 6.75 6.75 6.75 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pIC50 5.52 5.52 5.52 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pIC50 6.18 6.18 6.18 ChEMBL
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pIC50 6.96 6.96 6.96 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pIC50 6.62 6.62 6.62 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pIC50 6.35 6.35 6.35 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pIC50 8.13 8.13 8.13 ChEMBL