JNJ-18038683


SMILES Clc1ccc(cc1)c1nn(c2c1CCNCC2)Cc1ccccc1
InChIKey UKJPMZGILXATGT-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 3
Molecular weight (Da) 337.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
EP4 PE2R4 Mouse Prostanoid A pKi 6.64 6.64 6.64 ChEMBL
EP3 PE2R3 Mouse Prostanoid A pKi 10.17 10.17 10.17 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
EP3 PE2R3 Mouse Prostanoid A pIC50 8.8 8.8 8.8 ChEMBL