ONO-AE1-437


SMILES COCc1cccc(c1)C[C@@H](/C=C/[C@H]1[C@H](O)CC(=O)[C@@H]1CCSCCCC(=O)O)O
InChIKey ORSJUPRAHPZYRL-XHTUOEPPSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 3
Rotatable bonds 13
Molecular weight (Da) 436.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
EP4 PE2R4 Mouse Prostanoid A pKi 6.37 6.37 6.37 ChEMBL
EP3 PE2R3 Mouse Prostanoid A pKi 9.11 9.11 9.11 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
EP3 PE2R3 Mouse Prostanoid A pIC50 8.16 8.16 8.16 ChEMBL