CCK-8


SMILES None
InChIKey IZTQOLKUZKXIRV-YRVFCXMDSA-N
Sequence DYMGWMDF

Chemical properties

Hydrogen bond acceptors None
Hydrogen bond donors None
Rotatable bonds None
Molecular weight (Da)

Drug properties

Molecular type Peptide
Physiological/Surrogate Endogenous
Approved drug Yes

Database connections

Structure pdb 7EZK 7EZM 7XOU 7XOX 7EZH

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CCK2 GASR Rat Cholecystokinin A pKi 8.55 9.15 9.39 ChEMBL
CCK1 CCKAR Rat Cholecystokinin A pKi 8.06 9.36 10.05 ChEMBL
CCK1 CCKAR Human Cholecystokinin A pKi 9.55 9.55 9.55 ChEMBL
CCK2 GASR Rat Cholecystokinin A pKi 9.28 9.51 10.0 PDSP Ki database
CCK2 GASR Human Cholecystokinin A pKi 8.88 8.88 8.88 PDSP Ki database
CCK1 CCKAR Human Cholecystokinin A pKi 8.02 8.02 8.02 Drug Central
CCK2 GASR Human Cholecystokinin A pKi 8.02 8.02 8.02 Drug Central
CCK2 GASR Rat Cholecystokinin A pKi 8.03 8.03 8.03 Drug Central
CCK1 CCKAR Rat Cholecystokinin A pKi 8.0 8.0 8.0 Drug Central
CCK2 GASR Human Cholecystokinin A pKi 9.19 9.43 9.55 ChEMBL
CCK1 CCKAR Guinea pig Cholecystokinin A pKi 9.15 9.27 9.55 ChEMBL
CCK1 CCKAR Guinea pig Cholecystokinin A pKi 8.02 8.02 8.02 Drug Central
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CCK2 GASR Human Cholecystokinin A pIC50 9.9 9.95 10.0 Guide to Pharmacology
CCK1 CCKAR Rat Cholecystokinin A pIC50 8.55 8.55 8.55 Guide to Pharmacology
CCK2 GASR Rat Cholecystokinin A pIC50 8.22 8.39 9.0 ChEMBL
CCK2 GASR Rat Cholecystokinin A pEC50 9.2 9.2 9.2 ChEMBL
CCK1 CCKAR Rat Cholecystokinin A pIC50 8.97 9.39 10.0 ChEMBL
CCK1 CCKAR Human Cholecystokinin A pIC50 8.88 9.33 9.95 ChEMBL
CCK1 CCKAR Human Cholecystokinin A pEC50 7.55 8.87 10.36 ChEMBL
CCK2 GASR Mouse Cholecystokinin A pIC50 8.02 8.02 8.02 Drug Central
CCK2 GASR Human Cholecystokinin A pIC50 8.09 9.38 9.92 ChEMBL
CCK2 GASR Human Cholecystokinin A pEC50 7.57 8.95 10.3 ChEMBL
CCK2 GASR Mouse Cholecystokinin A pIC50 8.89 9.41 9.52 ChEMBL
CCK1 CCKAR Guinea pig Cholecystokinin A pIC50 9.4 9.48 9.55 ChEMBL