adriforant


SMILES CN[C@@H]1CCN(C1)c1cc(NCC2CC2)nc(n1)N
InChIKey ISBHYKVAFKTATD-SNVBAGLBSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 3
Rotatable bonds 5
Molecular weight (Da) 262.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug Yes

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Bovine Dopamine A pKi 5.09 5.22 5.36 ChEMBL
D4 DRD4 Human Dopamine A pKi 8.33 8.57 8.8 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.29 7.09 7.89 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.27 7.74 8.19 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database