pindolol


SMILES OC(COc1cccc2c1cc[nH]2)CNC(C)C
InChIKey JZQKKSLKJUAGIC-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 3
Rotatable bonds 6
Molecular weight (Da) 248.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug Yes

Database connections

Ligand site mutations β2 5-HT1A 5-HT1B 5-HT1D 5-HT1E 5-HT1F

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu5 GRM5 Human Metabotropic glutamate C pIC50 5.6 7.05 8.5 Guide to Pharmacology
M5 ACM5 Human Acetylcholine (muscarinic) A pEC50 5.58 5.58 5.58 ChEMBL
mGlu5 GRM5 Human Metabotropic glutamate C pEC50 5.58 7.11 8.63 ChEMBL
mGlu5 GRM5 Mouse Metabotropic glutamate C pIC50 3.87 3.87 3.87 ChEMBL