quinelorane


SMILES CCCN1CCC[C@H]2[C@H]1Cc1cnc(nc1C2)N
InChIKey TUFADSGTJUOBEH-ZWNOBZJWSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 2
Molecular weight (Da) 246.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu5 GRM5 Rat Metabotropic glutamate C pKi 7.72 7.72 7.72 Guide to Pharmacology
mGlu5 GRM5 Rat Metabotropic glutamate C pKi 7.72 7.72 7.72 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu5 GRM5 Human Metabotropic glutamate C pIC50 7.11 7.11 7.11 Guide to Pharmacology