ASP4058


SMILES C[C@@H](C(F)(F)F)Oc1ccc(cc1C(F)(F)F)c1onc(n1)c1ccc2c(c1)nc[nH]2
InChIKey NJNXCJPSMWKXHO-VIFPVBQESA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 442.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug Yes

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Bovine Dopamine A pKi 4.77 4.83 4.89 ChEMBL
D4 DRD4 Human Dopamine A pKi 6.28 6.49 6.7 ChEMBL
D3 DRD3 Human Dopamine A pKi 5.06 5.3 5.54 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.1 5.56 5.96 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database