GPCRdb

sulpiride

SMILES	CCN1CCCC1CNC(=O)c1cc(ccc1OC)S(=O)(=O)N
InChIKey	BGRJTUBHPOOWDU-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors	5
Hydrogen bond donors	2
Rotatable bonds	6
Molecular weight (Da)	341.1

Drug properties

Molecular type	Small molecule
Endogenous/Surrogate	Surrogate
Approved drug	Yes

Database connections

PubChem Guide To Pharmacology ChEMBL_compound_ids DrugBank Drug Central PubChem Guide To Pharmacology ChEMBL_compound_ids Drug Central DrugBank PubChem Guide To Pharmacology ChEMBL_compound_ids PubChem GPCRdb
Ligand site mutations	D₁ D₂ D₄

Bioactivities

Affinity
Potency

Receptor					Activity				Source
GTP	Uniprot	Species	Family	Class	Type	Min	Avg	Max	Database
OX₂	OX2R	Human	Orexin	A	pKi	8.3	8.3	8.3	Guide to Pharmacology
OX₁	OX1R	Human	Orexin	A	pKi	8.2	8.2	8.2	ChEMBL
OX₁	OX1R	Human	Orexin	A	pKi	5.3	5.3	5.3	Guide to Pharmacology
OX₂	OX2R	Human	Orexin	A	pKi	8.2	8.2	8.2	ChEMBL

Receptor					Activity				Source
GTP	Uniprot	Species	Family	Class	Type	Min	Avg	Max	Database