semaglutide


SMILES None
InChIKey DLSWIYLPEUIQAV-CCUURXOWSA-N
Sequence HAEGTFTSDVSSYLEGQAAKEFIAWLVRGRG

Chemical properties

Hydrogen bond acceptors None
Hydrogen bond donors None
Rotatable bonds None
Molecular weight (Da)

Drug properties

Molecular type Peptide
Endogenous/Surrogate Surrogate
Approved drug Yes

Database connections

Structure pdb 7KI0

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pKi 7.72 7.72 7.72 ChEMBL
κ OPRK Human Opioid A pKi 7.91 7.91 7.91 ChEMBL
μ OPRM Human Opioid A pKi 8.43 8.43 8.43 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pEC50 7.21 7.21 7.21 ChEMBL
κ OPRK Human Opioid A pEC50 5.99 5.99 5.99 ChEMBL
μ OPRM Human Opioid A pEC50 6.96 6.96 6.96 ChEMBL