macimorelin


SMILES O=CN[C@@H](Cc1c[nH]c2c1cccc2)NC(=O)[C@H](NC(=O)C(N)(C)C)Cc1c[nH]c2c1cccc2
InChIKey UJVDJAPJQWZRFR-DHIUTWEWSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 6
Rotatable bonds 10
Molecular weight (Da) 474.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug Yes

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 5.7 5.7 5.7 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.4 7.4 7.4 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 5.4 5.4 5.4 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database