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Ligand source activities (1 row/activity)

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Ligands (move mouse cursor over ligand name to see structure)					Receptor	Activity									Chemical information
Sel. page	Common name	GPCRdb ID	Reference ligand	Vendors	Species	Assay Type	Activity Type	Activity Relation	Activity Value	p-value (-log)	Fold selectivity	Tested GPCRs	Assay Description	Source	Mol weight	Rot Bonds	H don	H acc	LogP	Smiles	DOI
	118037818	134778	None	0	Human	Functional	pAC50	=	5.5	5.5	1	2	Agonist activity at RXFP2 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assayAgonist activity at RXFP2 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assay	ChEMBL	428	4	2	4	4.9	O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1ccc2c(c1)OCO2	nan
	CHEMBL3718470	134778	None	0	Human	Functional	pAC50	=	5.5	5.5	1	2	Agonist activity at RXFP2 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assayAgonist activity at RXFP2 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assay	ChEMBL	428	4	2	4	4.9	O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1ccc2c(c1)OCO2	nan
	90010773	133980	None	0	Human	Functional	pAC50	=	5.1	5.1	1	2	Agonist activity at RXFP2 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assayAgonist activity at RXFP2 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assay	ChEMBL	375	4	2	4	4.2	O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1ccno1	nan
	CHEMBL3715750	133980	None	0	Human	Functional	pAC50	=	5.1	5.1	1	2	Agonist activity at RXFP2 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assayAgonist activity at RXFP2 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assay	ChEMBL	375	4	2	4	4.2	O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1ccno1	nan
	127024071	134094	None	0	Human	Functional	pAC50	=	5.0	5.0	-	1	Agonist activity at RXFP2 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assayAgonist activity at RXFP2 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assay	ChEMBL	361	4	3	2	4.9	O=C(Nc1ccc2cc[nH]c2c1)c1ccccc1NC(=O)C1CCCCC1	nan
	CHEMBL3716158	134094	None	0	Human	Functional	pAC50	=	5.0	5.0	-	1	Agonist activity at RXFP2 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assayAgonist activity at RXFP2 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assay	ChEMBL	361	4	3	2	4.9	O=C(Nc1ccc2cc[nH]c2c1)c1ccccc1NC(=O)C1CCCCC1	nan
	12503	1127	None	0	Human	Functional	pEC50	=	6.4	6.4	-	1	Determined in a HTRF cAMP assay using HEK-RXFP2 cells.Determined in a HTRF cAMP assay using HEK-RXFP2 cells.	Guide to Pharmacology	787	5	1	5	6.6	FC(F)(F)OC1=CC(I)=C(OCC(=O)N2CCN3[C@@H](C2)C(=O)NC4=C(C=C(C=C4)C5=CC(=CC(=C5)C(F)(F)F)C(F)(F)F)C3=O)C=C1	36333465
	167993647	1127	None	0	Human	Functional	pEC50	=	6.4	6.4	-	1	Determined in a HTRF cAMP assay using HEK-RXFP2 cells.Determined in a HTRF cAMP assay using HEK-RXFP2 cells.	Guide to Pharmacology	787	5	1	5	6.6	FC(F)(F)OC1=CC(I)=C(OCC(=O)N2CCN3[C@@H](C2)C(=O)NC4=C(C=C(C=C4)C5=CC(=CC(=C5)C(F)(F)F)C(F)(F)F)C3=O)C=C1	36333465
	11914	2045	None	0	Human	Functional	pEC50	=	10	10.0	-	1	Receptor activationReceptor activation	Guide to Pharmacology		None	None	None		None	22654853
	8346	202	None	0	Human	Functional	pEC50	=	6	6.0	-165	2	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	21878627
	1989	3305	None	0	Human	Functional	pEC50	=	9.1	9.1	-17	3	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	18434306

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Ligands (move mouse cursor over ligand name to see structure)					Receptor	Activity									Chemical information
Sel. page	Common name	GPCRdb ID	Reference ligand	Vendors	Species	Assay Type	Activity Type	Activity Relation	Activity Value	p-value (-log)	Fold selectivity	Tested GPCRs	Assay Description	Source	Mol weight	Rot Bonds	H don	H acc	LogP	Smiles	DOI
	11913	2731	None	0	Human	Binding	pKd	=	8.7	8.7	-	1	Receptor binding affinityReceptor binding affinity	Guide to Pharmacology		None	None	None		None	24056075
	1995	2044	None	0	Human	Binding	pKd	=	10.4	10.4	16982	2	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	18434306
	3875	1599	None	0	Human	Binding	pKd	=	9	9.0	-	1	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	18529069
	11914	2045	None	0	Human	Binding	pKi	=	7.8	7.8	-	1	Receptor bindingReceptor binding	Guide to Pharmacology		None	None	None		None	22654853
	3885	2046	None	0	Human	Binding	pKi	=	5.1	5.1	-	1	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	16547350
	8346	202	None	0	Human	Binding	pKi	=	6	6.0	-9	2	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	21878627
	8333	1279	None	0	Human	Binding	pKi	=	6.7	6.7	-	1	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	17120268
	8332	282	None	0	Human	Binding	pKi	=	8.3	8.3	-	1	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	20570702
	1989	3305	None	0	Human	Binding	pKi	=	8.4	8.4	-40	3	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	15649866
	1989	3305	None	0	Human	Binding	pKi	=	8.4	8.4	-40	3	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	18434306
	155817469	2047	None	0	Human	Binding	pKi	=	8.5	8.5	-	1	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	20560146
	4372	2047	None	0	Human	Binding	pKi	=	8.5	8.5	-	1	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	20560146
	8331	233	None	0	Human	Binding	pKi	=	8.6	8.6	-	1	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	20570702
	155817501	190	None	0	Human	Binding	pKi	=	8.7	8.7	-	1	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	18434306
	8330	190	None	0	Human	Binding	pKi	=	8.7	8.7	-	1	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	18434306
	134813893	214	None	0	Human	Binding	pKi	=	9.1	9.1	-	1	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	18434306
	8329	214	None	0	Human	Binding	pKi	=	9.1	9.1	-	1	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	18434306
	1995	2044	None	0	Human	Binding	pKi	=	9.5	9.5	16982	2	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	15649866
	1995	2044	None	0	Human	Binding	pKi	=	9.5	9.5	16982	2	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	18434306
	1990	3307	None	0	Human	Binding	pKi	None	7	7.0	-81	4	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	16411781
	1994	3302	None	0	Human	Binding	pKi	None	7.8	7.8	-39	2	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	15649866
	1992	3303	None	0	Human	Binding	pKi	None	7.9	7.9	-15	2	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	15649866
	1988	3306	None	0	Human	Binding	pKi	None	8.8	8.8	-	1	UnclassifiedUnclassified	Guide to Pharmacology		None	None	None		None	16411781

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Ligand source activities (1 row/activity)