Ligand source activities (1 row/activity)
| Ligands (move mouse cursor over ligand name to see structure) | Receptor | Activity | Chemical information | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Sel. page | Common name
| GPCRdb ID
| Reference ligand
| Vendors | Species
| Assay Type
| Activity Type
| Activity Relation
| Activity Value | p-value (-log) | Fold selectivity | Tested GPCRs | Assay Description
| Source
| Mol weight | Rot Bonds | H don | H acc | LogP | Smiles
| DOI
| |
Ligands (move mouse cursor over ligand name to see structure)
| Receptor
| Activity
| Chemical information
| |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sel. page | Common name
| GPCRdb ID
| Reference ligand
| Vendors | Species
| Assay Type
| Activity Type
| Activity Relation
| Activity Value | p-value (-log) | Fold selectivity | Tested GPCRs | Assay Description
| Source
| Mol weight | Rot Bonds | H don | H acc | LogP | Smiles
| DOI
| |
| 155531953 | 171849 | None | 0 | Human | Functional | pEC50 | = | 5.9 | 5.9 | -2 | 3 | Agonist activity at chemR23 expressed in human CAL1 cells assessed as increase in intracellular calcium ion concentrationAgonist activity at chemR23 expressed in human CAL1 cells assessed as increase in intracellular calcium ion concentration |
ChEMBL | 438 | 8 | 1 | 6 | 6.0 | CCCCN(c1nc2ccccc2o1)[C@H](C)c1ccc(-c2ccccc2-c2nnn[nH]2)cc1 | 10.1016/j.bmc.2019.115091 | ||
| CHEMBL4467290 | 171849 | None | 0 | Human | Functional | pEC50 | = | 5.9 | 5.9 | -2 | 3 | Agonist activity at chemR23 expressed in human CAL1 cells assessed as increase in intracellular calcium ion concentrationAgonist activity at chemR23 expressed in human CAL1 cells assessed as increase in intracellular calcium ion concentration |
ChEMBL | 438 | 8 | 1 | 6 | 6.0 | CCCCN(c1nc2ccccc2o1)[C@H](C)c1ccc(-c2ccccc2-c2nnn[nH]2)cc1 | 10.1016/j.bmc.2019.115091 | ||
| 155563693 | 175498 | None | 0 | Human | Functional | pEC50 | = | 5.9 | 5.9 | 36 | 2 | Agonist activity at chemR23 expressed in human CAL1 cells assessed as increase in intracellular calcium ion concentrationAgonist activity at chemR23 expressed in human CAL1 cells assessed as increase in intracellular calcium ion concentration |
ChEMBL | 524 | 10 | 3 | 7 | 5.5 | CCCCN(c1nc2cc(CNC(=O)NC)ccc2o1)[C@H](C)c1ccc(-c2ccccc2-c2nnn[nH]2)cc1 | 10.1016/j.bmc.2019.115091 | ||
| CHEMBL4575422 | 175498 | None | 0 | Human | Functional | pEC50 | = | 5.9 | 5.9 | 36 | 2 | Agonist activity at chemR23 expressed in human CAL1 cells assessed as increase in intracellular calcium ion concentrationAgonist activity at chemR23 expressed in human CAL1 cells assessed as increase in intracellular calcium ion concentration |
ChEMBL | 524 | 10 | 3 | 7 | 5.5 | CCCCN(c1nc2cc(CNC(=O)NC)ccc2o1)[C@H](C)c1ccc(-c2ccccc2-c2nnn[nH]2)cc1 | 10.1016/j.bmc.2019.115091 | ||
| 11332190 | 909 | None | 15 | Human | Functional | pEC50 | = | 6.9 | 6.9 | -22 | 2 | Agonist activity at Wild type CMKL1 (unknown origin) expressed in COS-7 cells assessed as accumulation of inositol phosphate incubated for 3 hrs by liquid scintillation counting methodAgonist activity at Wild type CMKL1 (unknown origin) expressed in COS-7 cells assessed as accumulation of inositol phosphate incubated for 3 hrs by liquid scintillation counting method |
ChEMBL | None | None | None | None | 10.1021/acs.jmedchem.0c01804 | ||||
| 156598973 | 909 | None | 15 | Human | Functional | pEC50 | = | 6.9 | 6.9 | -22 | 2 | Agonist activity at Wild type CMKL1 (unknown origin) expressed in COS-7 cells assessed as accumulation of inositol phosphate incubated for 3 hrs by liquid scintillation counting methodAgonist activity at Wild type CMKL1 (unknown origin) expressed in COS-7 cells assessed as accumulation of inositol phosphate incubated for 3 hrs by liquid scintillation counting method |
ChEMBL | None | None | None | None | 10.1021/acs.jmedchem.0c01804 | ||||
| 3422 | 909 | None | 15 | Human | Functional | pEC50 | = | 6.9 | 6.9 | -22 | 2 | Agonist activity at Wild type CMKL1 (unknown origin) expressed in COS-7 cells assessed as accumulation of inositol phosphate incubated for 3 hrs by liquid scintillation counting methodAgonist activity at Wild type CMKL1 (unknown origin) expressed in COS-7 cells assessed as accumulation of inositol phosphate incubated for 3 hrs by liquid scintillation counting method |
ChEMBL | None | None | None | None | 10.1021/acs.jmedchem.0c01804 | ||||
| CHEMBL5081975 | 909 | None | 15 | Human | Functional | pEC50 | = | 6.9 | 6.9 | -22 | 2 | Agonist activity at Wild type CMKL1 (unknown origin) expressed in COS-7 cells assessed as accumulation of inositol phosphate incubated for 3 hrs by liquid scintillation counting methodAgonist activity at Wild type CMKL1 (unknown origin) expressed in COS-7 cells assessed as accumulation of inositol phosphate incubated for 3 hrs by liquid scintillation counting method |
ChEMBL | None | None | None | None | 10.1021/acs.jmedchem.0c01804 | ||||
| 11332190 | 909 | None | 15 | Human | Functional | pEC50 | = | 6.9 | 6.9 | -22 | 2 | Agonist activity at Wild type CMKL1 (unknown origin) expressed in COS-7 cells assessed as accumulation of inositol phosphate incubated for 3 hrs by liquid scintillation counting methodAgonist activity at Wild type CMKL1 (unknown origin) expressed in COS-7 cells assessed as accumulation of inositol phosphate incubated for 3 hrs by liquid scintillation counting method |
ChEMBL | None | None | None | None | 10.1021/acs.jmedchem.0c01804 | ||||
| 156598973 | 909 | None | 15 | Human | Functional | pEC50 | = | 6.9 | 6.9 | -22 | 2 | Agonist activity at Wild type CMKL1 (unknown origin) expressed in COS-7 cells assessed as accumulation of inositol phosphate incubated for 3 hrs by liquid scintillation counting methodAgonist activity at Wild type CMKL1 (unknown origin) expressed in COS-7 cells assessed as accumulation of inositol phosphate incubated for 3 hrs by liquid scintillation counting method |
ChEMBL | None | None | None | None | 10.1021/acs.jmedchem.0c01804 | ||||
| 3422 | 909 | None | 15 | Human | Functional | pEC50 | = | 6.9 | 6.9 | -22 | 2 | Agonist activity at Wild type CMKL1 (unknown origin) expressed in COS-7 cells assessed as accumulation of inositol phosphate incubated for 3 hrs by liquid scintillation counting methodAgonist activity at Wild type CMKL1 (unknown origin) expressed in COS-7 cells assessed as accumulation of inositol phosphate incubated for 3 hrs by liquid scintillation counting method |
ChEMBL | None | None | None | None | 10.1021/acs.jmedchem.0c01804 | ||||
| CHEMBL5081975 | 909 | None | 15 | Human | Functional | pEC50 | = | 6.9 | 6.9 | -22 | 2 | Agonist activity at Wild type CMKL1 (unknown origin) expressed in COS-7 cells assessed as accumulation of inositol phosphate incubated for 3 hrs by liquid scintillation counting methodAgonist activity at Wild type CMKL1 (unknown origin) expressed in COS-7 cells assessed as accumulation of inositol phosphate incubated for 3 hrs by liquid scintillation counting method |
ChEMBL | None | None | None | None | 10.1021/acs.jmedchem.0c01804 | ||||
| CHEMBL5088494 | 217653 | None | 0 | Human | Functional | pEC50 | = | 6.8 | 6.8 | - | 1 | Agonist activity at Wild type CMKL1 (unknown origin) expressed in COS-7 cells assessed as accumulation of inositol phosphate incubated for 3 hrs by liquid scintillation counting methodAgonist activity at Wild type CMKL1 (unknown origin) expressed in COS-7 cells assessed as accumulation of inositol phosphate incubated for 3 hrs by liquid scintillation counting method |
ChEMBL | None | None | None | C[C@@H]1NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC(=O)[C@@H]2CCCN2C(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](N)Cc2ccc(O)cc2)CSSC[C@@H](C(=O)O)NC(=O)[C@H](Cc2ccccc2)NC1=O | 10.1021/acs.jmedchem.0c01804 | ||||
| 155538662 | 172520 | None | 0 | Human | Functional | pEC50 | = | 5.8 | 5.8 | 2 | 2 | Agonist activity at chemR23 expressed in human CAL1 cells assessed as increase in intracellular calcium ion concentrationAgonist activity at chemR23 expressed in human CAL1 cells assessed as increase in intracellular calcium ion concentration |
ChEMBL | 495 | 9 | 2 | 7 | 6.0 | CCCCN(c1nc2cc(NC(C)=O)ccc2o1)[C@H](C)c1ccc(-c2ccccc2-c2nnn[nH]2)cc1 | 10.1016/j.bmc.2019.115091 | ||
| CHEMBL4476788 | 172520 | None | 0 | Human | Functional | pEC50 | = | 5.8 | 5.8 | 2 | 2 | Agonist activity at chemR23 expressed in human CAL1 cells assessed as increase in intracellular calcium ion concentrationAgonist activity at chemR23 expressed in human CAL1 cells assessed as increase in intracellular calcium ion concentration |
ChEMBL | 495 | 9 | 2 | 7 | 6.0 | CCCCN(c1nc2cc(NC(C)=O)ccc2o1)[C@H](C)c1ccc(-c2ccccc2-c2nnn[nH]2)cc1 | 10.1016/j.bmc.2019.115091 | ||
| CHEMBL5088494 | 217653 | None | 0 | Human | Functional | pEC50 | = | 6.8 | 6.8 | - | 1 | Agonist activity at Wild type CMKL1 (unknown origin) expressed in COS-7 cells assessed as accumulation of inositol phosphate incubated for 3 hrs by liquid scintillation counting methodAgonist activity at Wild type CMKL1 (unknown origin) expressed in COS-7 cells assessed as accumulation of inositol phosphate incubated for 3 hrs by liquid scintillation counting method |
ChEMBL | None | None | None | C[C@@H]1NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC(=O)[C@@H]2CCCN2C(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](N)Cc2ccc(O)cc2)CSSC[C@@H](C(=O)O)NC(=O)[C@H](Cc2ccccc2)NC1=O | 10.1021/acs.jmedchem.0c01804 | ||||
| CHEMBL5082551 | 217298 | None | 0 | Human | Functional | pEC50 | = | 7.7 | 7.7 | - | 1 | Agonist activity at wild type CMKL1 (unknown origin) expressed in COS-7 cells assessed as increase in calcium flux measured for 40 sec by Fluo-2 AM dye based assayAgonist activity at wild type CMKL1 (unknown origin) expressed in COS-7 cells assessed as increase in calcium flux measured for 40 sec by Fluo-2 AM dye based assay |
ChEMBL | None | None | None | C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)O | 10.1021/acs.jmedchem.0c01804 | ||||
| 168275711 | 190326 | None | 0 | Human | Functional | pEC50 | = | 6.7 | 6.7 | - | 1 | Agonist activity at human ChemR23 expressed in CAL-1 assessed as increase in calcium mobilizationAgonist activity at human ChemR23 expressed in CAL-1 assessed as increase in calcium mobilization |
ChEMBL | 635 | 11 | 2 | 9 | 6.0 | Cc1ccc(-c2nc(=O)s[nH]2)c(-c2ccc([C@@H](C)N(CC3CC3)c3nc(C(=O)NS(=O)(=O)C4CC4)c(C4CC4)s3)cc2)c1 | 10.1016/j.bmc.2021.116587 | ||
| CHEMBL5174724 | 190326 | None | 0 | Human | Functional | pEC50 | = | 6.7 | 6.7 | - | 1 | Agonist activity at human ChemR23 expressed in CAL-1 assessed as increase in calcium mobilizationAgonist activity at human ChemR23 expressed in CAL-1 assessed as increase in calcium mobilization |
ChEMBL | 635 | 11 | 2 | 9 | 6.0 | Cc1ccc(-c2nc(=O)s[nH]2)c(-c2ccc([C@@H](C)N(CC3CC3)c3nc(C(=O)NS(=O)(=O)C4CC4)c(C4CC4)s3)cc2)c1 | 10.1016/j.bmc.2021.116587 | ||
| 168293038 | 192232 | None | 0 | Human | Functional | pEC50 | = | 6.7 | 6.7 | - | 1 | Agonist activity at human ChemR23 expressed in CAL-1 assessed as increase in calcium mobilizationAgonist activity at human ChemR23 expressed in CAL-1 assessed as increase in calcium mobilization |
ChEMBL | 613 | 10 | 2 | 9 | 5.3 | Cc1sc(N(CC2CC2)[C@H](C)c2ccc(-c3cc(Cl)ccc3-c3nc(=O)o[nH]3)cc2)nc1C(=O)NS(=O)(=O)C1CC1 | 10.1016/j.bmc.2021.116587 | ||
| CHEMBL5203480 | 192232 | None | 0 | Human | Functional | pEC50 | = | 6.7 | 6.7 | - | 1 | Agonist activity at human ChemR23 expressed in CAL-1 assessed as increase in calcium mobilizationAgonist activity at human ChemR23 expressed in CAL-1 assessed as increase in calcium mobilization |
ChEMBL | 613 | 10 | 2 | 9 | 5.3 | Cc1sc(N(CC2CC2)[C@H](C)c2ccc(-c3cc(Cl)ccc3-c3nc(=O)o[nH]3)cc2)nc1C(=O)NS(=O)(=O)C1CC1 | 10.1016/j.bmc.2021.116587 | ||
| CHEMBL5077507 | 216989 | None | 0 | Human | Functional | pEC50 | = | 6.7 | 6.7 | - | 1 | Agonist activity at wild type CMKL1 (unknown origin) expressed in COS-7 cells assessed as increase in calcium flux measured for 40 sec by Fluo-2 AM dye based assayAgonist activity at wild type CMKL1 (unknown origin) expressed in COS-7 cells assessed as increase in calcium flux measured for 40 sec by Fluo-2 AM dye based assay |
ChEMBL | None | None | None | CC(C)C[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CO)C(=O)O | 10.1021/acs.jmedchem.0c01804 | ||||
| CHEMBL5077507 | 216989 | None | 0 | Human | Functional | pEC50 | = | 6.7 | 6.7 | - | 1 | Agonist activity at wild type CMKL1 (unknown origin) expressed in COS-7 cells assessed as increase in calcium flux measured for 40 sec by Fluo-2 AM dye based assayAgonist activity at wild type CMKL1 (unknown origin) expressed in COS-7 cells assessed as increase in calcium flux measured for 40 sec by Fluo-2 AM dye based assay |
ChEMBL | None | None | None | CC(C)C[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CO)C(=O)O | 10.1021/acs.jmedchem.0c01804 | ||||
| CHEMBL5082551 | 217298 | None | 0 | Human | Functional | pEC50 | = | 7.7 | 7.7 | - | 1 | Agonist activity at wild type CMKL1 (unknown origin) expressed in COS-7 cells assessed as increase in calcium flux measured for 40 sec by Fluo-2 AM dye based assayAgonist activity at wild type CMKL1 (unknown origin) expressed in COS-7 cells assessed as increase in calcium flux measured for 40 sec by Fluo-2 AM dye based assay |
ChEMBL | None | None | None | C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)O | 10.1021/acs.jmedchem.0c01804 | ||||
| 168291719 | 192067 | None | 0 | Human | Functional | pEC50 | = | 6.7 | 6.7 | - | 1 | Agonist activity at human ChemR23 expressed in CAL-1 assessed as increase in calcium mobilizationAgonist activity at human ChemR23 expressed in CAL-1 assessed as increase in calcium mobilization |
ChEMBL | 587 | 9 | 2 | 9 | 4.8 | Cc1sc(N(CC2CC2)[C@H](C)c2ccc(-c3cc(Cl)ccc3-c3nc(=O)o[nH]3)cc2)nc1C(=O)NS(C)(=O)=O | 10.1016/j.bmc.2021.116587 | ||
| CHEMBL5200919 | 192067 | None | 0 | Human | Functional | pEC50 | = | 6.7 | 6.7 | - | 1 | Agonist activity at human ChemR23 expressed in CAL-1 assessed as increase in calcium mobilizationAgonist activity at human ChemR23 expressed in CAL-1 assessed as increase in calcium mobilization |
ChEMBL | 587 | 9 | 2 | 9 | 4.8 | Cc1sc(N(CC2CC2)[C@H](C)c2ccc(-c3cc(Cl)ccc3-c3nc(=O)o[nH]3)cc2)nc1C(=O)NS(C)(=O)=O | 10.1016/j.bmc.2021.116587 | ||
| 168269858 | 190084 | None | 0 | Human | Functional | pEC50 | = | 6.7 | 6.7 | - | 1 | Agonist activity at human ChemR23 expressed in CAL-1 assessed as increase in calcium mobilizationAgonist activity at human ChemR23 expressed in CAL-1 assessed as increase in calcium mobilization |
ChEMBL | 642 | 13 | 2 | 8 | 6.2 | CCONC(=O)c1ccc(Cl)cc1-c1ccc([C@@H](C)N(CC2CC2)c2nc(C(=O)NS(=O)(=O)C3CC3)c(C3CC3)s2)cc1 | 10.1016/j.bmc.2021.116587 | ||
| CHEMBL5170854 | 190084 | None | 0 | Human | Functional | pEC50 | = | 6.7 | 6.7 | - | 1 | Agonist activity at human ChemR23 expressed in CAL-1 assessed as increase in calcium mobilizationAgonist activity at human ChemR23 expressed in CAL-1 assessed as increase in calcium mobilization |
ChEMBL | 642 | 13 | 2 | 8 | 6.2 | CCONC(=O)c1ccc(Cl)cc1-c1ccc([C@@H](C)N(CC2CC2)c2nc(C(=O)NS(=O)(=O)C3CC3)c(C3CC3)s2)cc1 | 10.1016/j.bmc.2021.116587 | ||
| 168292803 | 192172 | None | 0 | Human | Functional | pEC50 | = | 7.7 | 7.7 | - | 1 | Inhibition of human ChemR23 expressed in CAL-1 cells assessed as receptor internalizationInhibition of human ChemR23 expressed in CAL-1 cells assessed as receptor internalization |
ChEMBL | 931 | 32 | 2 | 14 | 6.7 | C[C@H](c1ccc(-c2cc(Cl)ccc2C(=O)NCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-])cc1)N(CC1CC1)c1nc(C(=O)NS(=O)(=O)C2CC2)c(C2CC2)s1 | 10.1016/j.bmc.2021.116587 | ||
| CHEMBL5202580 | 192172 | None | 0 | Human | Functional | pEC50 | = | 7.7 | 7.7 | - | 1 | Inhibition of human ChemR23 expressed in CAL-1 cells assessed as receptor internalizationInhibition of human ChemR23 expressed in CAL-1 cells assessed as receptor internalization |
ChEMBL | 931 | 32 | 2 | 14 | 6.7 | C[C@H](c1ccc(-c2cc(Cl)ccc2C(=O)NCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-])cc1)N(CC1CC1)c1nc(C(=O)NS(=O)(=O)C2CC2)c(C2CC2)s1 | 10.1016/j.bmc.2021.116587 | ||
| 168292522 | 192151 | None | 0 | Human | Functional | pEC50 | = | 6.7 | 6.7 | - | 1 | Agonist activity at human ChemR23 expressed in CAL-1 assessed as increase in calcium mobilizationAgonist activity at human ChemR23 expressed in CAL-1 assessed as increase in calcium mobilization |
ChEMBL | 639 | 11 | 2 | 9 | 5.9 | C[C@H](c1ccc(-c2cc(Cl)ccc2-c2nc(=O)o[nH]2)cc1)N(CC1CC1)c1nc(C(=O)NS(=O)(=O)C2CC2)c(C2CC2)s1 | 10.1016/j.bmc.2021.116587 | ||
| CHEMBL5202223 | 192151 | None | 0 | Human | Functional | pEC50 | = | 6.7 | 6.7 | - | 1 | Agonist activity at human ChemR23 expressed in CAL-1 assessed as increase in calcium mobilizationAgonist activity at human ChemR23 expressed in CAL-1 assessed as increase in calcium mobilization |
ChEMBL | 639 | 11 | 2 | 9 | 5.9 | C[C@H](c1ccc(-c2cc(Cl)ccc2-c2nc(=O)o[nH]2)cc1)N(CC1CC1)c1nc(C(=O)NS(=O)(=O)C2CC2)c(C2CC2)s1 | 10.1016/j.bmc.2021.116587 | ||
| 155519637 | 170525 | None | 0 | Human | Functional | pEC50 | = | 5.6 | 5.6 | - | 1 | Agonist activity at chemR23 expressed in human CAL1 cells assessed as increase in intracellular calcium ion concentrationAgonist activity at chemR23 expressed in human CAL1 cells assessed as increase in intracellular calcium ion concentration |
ChEMBL | 509 | 10 | 2 | 7 | 5.3 | CCCCN(c1nc2cc(CC(=O)NC)ccc2o1)[C@H](C)c1ccc(-c2ccccc2-c2nnn[nH]2)cc1 | 10.1016/j.bmc.2019.115091 | ||
| CHEMBL4448308 | 170525 | None | 0 | Human | Functional | pEC50 | = | 5.6 | 5.6 | - | 1 | Agonist activity at chemR23 expressed in human CAL1 cells assessed as increase in intracellular calcium ion concentrationAgonist activity at chemR23 expressed in human CAL1 cells assessed as increase in intracellular calcium ion concentration |
ChEMBL | 509 | 10 | 2 | 7 | 5.3 | CCCCN(c1nc2cc(CC(=O)NC)ccc2o1)[C@H](C)c1ccc(-c2ccccc2-c2nnn[nH]2)cc1 | 10.1016/j.bmc.2019.115091 | ||
| 155530073 | 171595 | None | 0 | Human | Functional | pEC50 | = | 5.6 | 5.6 | 10 | 2 | Agonist activity at chemR23 expressed in human CAL1 cells assessed as increase in intracellular calcium ion concentrationAgonist activity at chemR23 expressed in human CAL1 cells assessed as increase in intracellular calcium ion concentration |
ChEMBL | 438 | 8 | 1 | 6 | 6.0 | CCCCN(c1nc2ccccc2o1)C(C)c1ccc(-c2ccccc2-c2nnn[nH]2)cc1 | 10.1016/j.bmc.2019.115091 | ||
| CHEMBL4463797 | 171595 | None | 0 | Human | Functional | pEC50 | = | 5.6 | 5.6 | 10 | 2 | Agonist activity at chemR23 expressed in human CAL1 cells assessed as increase in intracellular calcium ion concentrationAgonist activity at chemR23 expressed in human CAL1 cells assessed as increase in intracellular calcium ion concentration |
ChEMBL | 438 | 8 | 1 | 6 | 6.0 | CCCCN(c1nc2ccccc2o1)C(C)c1ccc(-c2ccccc2-c2nnn[nH]2)cc1 | 10.1016/j.bmc.2019.115091 | ||
| 155519352 | 170544 | None | 6 | Human | Functional | pEC50 | = | 6.6 | 6.6 | -1 | 2 | Agonist activity at chemR23 expressed in human CAL1 cells assessed as increase in intracellular calcium ion concentrationAgonist activity at chemR23 expressed in human CAL1 cells assessed as increase in intracellular calcium ion concentration |
ChEMBL | 495 | 9 | 2 | 7 | 5.4 | CCCCN(c1nc2cc(C(=O)NC)ccc2o1)[C@H](C)c1ccc(-c2ccccc2-c2nnn[nH]2)cc1 | 10.1016/j.bmc.2019.115091 | ||
| CHEMBL4448632 | 170544 | None | 6 | Human | Functional | pEC50 | = | 6.6 | 6.6 | -1 | 2 | Agonist activity at chemR23 expressed in human CAL1 cells assessed as increase in intracellular calcium ion concentrationAgonist activity at chemR23 expressed in human CAL1 cells assessed as increase in intracellular calcium ion concentration |
ChEMBL | 495 | 9 | 2 | 7 | 5.4 | CCCCN(c1nc2cc(C(=O)NC)ccc2o1)[C@H](C)c1ccc(-c2ccccc2-c2nnn[nH]2)cc1 | 10.1016/j.bmc.2019.115091 | ||
| CHEMBL5085505 | 217459 | None | 0 | Human | Functional | pEC50 | = | 6.6 | 6.6 | - | 1 | Agonist activity at wild type CMKL1 (unknown origin) expressed in COS-7 cells assessed as increase in calcium flux measured for 40 sec by Fluo-2 AM dye based assayAgonist activity at wild type CMKL1 (unknown origin) expressed in COS-7 cells assessed as increase in calcium flux measured for 40 sec by Fluo-2 AM dye based assay |
ChEMBL | None | None | None | CC(C)C[C@H](NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CO)C(=O)O | 10.1021/acs.jmedchem.0c01804 | ||||
| CHEMBL5085505 | 217459 | None | 0 | Human | Functional | pEC50 | = | 6.6 | 6.6 | - | 1 | Agonist activity at wild type CMKL1 (unknown origin) expressed in COS-7 cells assessed as increase in calcium flux measured for 40 sec by Fluo-2 AM dye based assayAgonist activity at wild type CMKL1 (unknown origin) expressed in COS-7 cells assessed as increase in calcium flux measured for 40 sec by Fluo-2 AM dye based assay |
ChEMBL | None | None | None | CC(C)C[C@H](NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CO)C(=O)O | 10.1021/acs.jmedchem.0c01804 | ||||
| CHEMBL5080998 | 217202 | None | 0 | Human | Functional | pEC50 | = | 7.5 | 7.5 | - | 1 | Agonist activity at wild type CMKL1 (unknown origin) expressed in COS-7 cells assessed as increase in calcium flux measured for 40 sec by Fluo-2 AM dye based assayAgonist activity at wild type CMKL1 (unknown origin) expressed in COS-7 cells assessed as increase in calcium flux measured for 40 sec by Fluo-2 AM dye based assay |
ChEMBL | None | None | None | C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)NCc1ccccc1 | 10.1021/acs.jmedchem.0c01804 | ||||
| CHEMBL5080998 | 217202 | None | 0 | Human | Functional | pEC50 | = | 7.5 | 7.5 | - | 1 | Agonist activity at wild type CMKL1 (unknown origin) expressed in COS-7 cells assessed as increase in calcium flux measured for 40 sec by Fluo-2 AM dye based assayAgonist activity at wild type CMKL1 (unknown origin) expressed in COS-7 cells assessed as increase in calcium flux measured for 40 sec by Fluo-2 AM dye based assay |
ChEMBL | None | None | None | C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)NCc1ccccc1 | 10.1021/acs.jmedchem.0c01804 | ||||
| CHEMBL5092307 | 217848 | None | 0 | Human | Functional | pEC50 | = | 7.4 | 7.4 | - | 1 | Agonist activity at Wild type CMKL1 (unknown origin) expressed in COS-7 cells assessed as accumulation of inositol phosphate incubated for 3 hrs by liquid scintillation counting methodAgonist activity at Wild type CMKL1 (unknown origin) expressed in COS-7 cells assessed as accumulation of inositol phosphate incubated for 3 hrs by liquid scintillation counting method |
ChEMBL | None | None | None | C[C@@H]1NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](NC(=O)[C@@H]2CCCN2C(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](N)Cc2ccc(O)cc2)CCSSC[C@@H](C(=O)O)NC(=O)[C@H](Cc2ccccc2)NC1=O | 10.1021/acs.jmedchem.0c01804 | ||||
| 168286108 | 191497 | None | 0 | Human | Functional | pEC50 | = | 6.4 | 6.4 | - | 1 | Agonist activity at human ChemR23 expressed in CAL-1 assessed as increase in calcium mobilizationAgonist activity at human ChemR23 expressed in CAL-1 assessed as increase in calcium mobilization |
ChEMBL | 510 | 8 | 2 | 7 | 5.8 | Cc1sc(N(CC2CC2)[C@H](C)c2ccc(-c3cc(Cl)ccc3-c3nc(=O)o[nH]3)cc2)nc1C(=O)O | 10.1016/j.bmc.2021.116587 | ||
| CHEMBL5192437 | 191497 | None | 0 | Human | Functional | pEC50 | = | 6.4 | 6.4 | - | 1 | Agonist activity at human ChemR23 expressed in CAL-1 assessed as increase in calcium mobilizationAgonist activity at human ChemR23 expressed in CAL-1 assessed as increase in calcium mobilization |
ChEMBL | 510 | 8 | 2 | 7 | 5.8 | Cc1sc(N(CC2CC2)[C@H](C)c2ccc(-c3cc(Cl)ccc3-c3nc(=O)o[nH]3)cc2)nc1C(=O)O | 10.1016/j.bmc.2021.116587 | ||
| 168284015 | 191360 | None | 0 | Human | Functional | pEC50 | = | 6.4 | 6.4 | - | 1 | Inhibition of human ChemR23 expressed in CAL-1 cells assessed as receptor internalizationInhibition of human ChemR23 expressed in CAL-1 cells assessed as receptor internalization |
ChEMBL | 1666 | 82 | 2 | 31 | 6.9 | C[C@H](c1ccc(-c2cc(Cl)ccc2C(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCOCCOCCOCCOCCN=[N+]=[N-])cc1)N(CC1CC1)c1nc(C(=O)NS(=O)(=O)C2CC2)c(C2CC2)s1 | 10.1016/j.bmc.2021.116587 | ||
| CHEMBL5190234 | 191360 | None | 0 | Human | Functional | pEC50 | = | 6.4 | 6.4 | - | 1 | Inhibition of human ChemR23 expressed in CAL-1 cells assessed as receptor internalizationInhibition of human ChemR23 expressed in CAL-1 cells assessed as receptor internalization |
ChEMBL | 1666 | 82 | 2 | 31 | 6.9 | C[C@H](c1ccc(-c2cc(Cl)ccc2C(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCOCCOCCOCCOCCN=[N+]=[N-])cc1)N(CC1CC1)c1nc(C(=O)NS(=O)(=O)C2CC2)c(C2CC2)s1 | 10.1016/j.bmc.2021.116587 | ||
| CHEMBL5092307 | 217848 | None | 0 | Human | Functional | pEC50 | = | 7.4 | 7.4 | - | 1 | Agonist activity at Wild type CMKL1 (unknown origin) expressed in COS-7 cells assessed as accumulation of inositol phosphate incubated for 3 hrs by liquid scintillation counting methodAgonist activity at Wild type CMKL1 (unknown origin) expressed in COS-7 cells assessed as accumulation of inositol phosphate incubated for 3 hrs by liquid scintillation counting method |
ChEMBL | None | None | None | C[C@@H]1NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](NC(=O)[C@@H]2CCCN2C(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](N)Cc2ccc(O)cc2)CCSSC[C@@H](C(=O)O)NC(=O)[C@H](Cc2ccccc2)NC1=O | 10.1021/acs.jmedchem.0c01804 | ||||
| 155537257 | 172370 | None | 0 | Human | Functional | pEC50 | = | 5.4 | 5.4 | 2 | 2 | Agonist activity at chemR23 expressed in human CAL1 cells assessed as increase in intracellular calcium ion concentrationAgonist activity at chemR23 expressed in human CAL1 cells assessed as increase in intracellular calcium ion concentration |
ChEMBL | 438 | 8 | 1 | 6 | 5.8 | CCCCN(Cc1ccc(-c2ccccc2-c2nnn[nH]2)cc1)c1nc2cc(C)ccc2o1 | 10.1016/j.bmc.2019.115091 | ||
| CHEMBL4474605 | 172370 | None | 0 | Human | Functional | pEC50 | = | 5.4 | 5.4 | 2 | 2 | Agonist activity at chemR23 expressed in human CAL1 cells assessed as increase in intracellular calcium ion concentrationAgonist activity at chemR23 expressed in human CAL1 cells assessed as increase in intracellular calcium ion concentration |
ChEMBL | 438 | 8 | 1 | 6 | 5.8 | CCCCN(Cc1ccc(-c2ccccc2-c2nnn[nH]2)cc1)c1nc2cc(C)ccc2o1 | 10.1016/j.bmc.2019.115091 | ||
Showing 1 to 50 of 318 entries
| Ligands (move mouse cursor over ligand name to see structure) | Receptor | Activity | Chemical information | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Sel. page | Common name
| GPCRdb ID
| Reference ligand
| Vendors | Species
| Assay Type
| Activity Type
| Activity Relation
| Activity Value | p-value (-log) | Fold selectivity | Tested GPCRs | Assay Description
| Source
| Mol weight | Rot Bonds | H don | H acc | LogP | Smiles
| DOI
| |
Ligands (move mouse cursor over ligand name to see structure)
| Receptor
| Activity
| Chemical information
| |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sel. page | Common name
| GPCRdb ID
| Reference ligand
| Vendors | Species
| Assay Type
| Activity Type
| Activity Relation
| Activity Value | p-value (-log) | Fold selectivity | Tested GPCRs | Assay Description
| Source
| Mol weight | Rot Bonds | H don | H acc | LogP | Smiles
| DOI
| |
| 10473088 | 3319 | None | 18 | Human | Binding | pEC50 | = | 9 | 9.0 | - | 1 | Antagonist activity at human CMKLR1Antagonist activity at human CMKLR1 |
ChEMBL | 350 | 13 | 4 | 4 | 2.9 | CC[C@H](/C=C/C=C\C[C@H](/C=C/C=C/C=C\[C@H](CCCC(=O)O)O)O)O | 10.1021/acs.jmedchem.3c01011 | ||
| 3333 | 3319 | None | 18 | Human | Binding | pEC50 | = | 9 | 9.0 | - | 1 | Antagonist activity at human CMKLR1Antagonist activity at human CMKLR1 |
ChEMBL | 350 | 13 | 4 | 4 | 2.9 | CC[C@H](/C=C/C=C\C[C@H](/C=C/C=C/C=C\[C@H](CCCC(=O)O)O)O)O | 10.1021/acs.jmedchem.3c01011 | ||
| CHEMBL1742483 | 3319 | None | 18 | Human | Binding | pEC50 | = | 9 | 9.0 | - | 1 | Antagonist activity at human CMKLR1Antagonist activity at human CMKLR1 |
ChEMBL | 350 | 13 | 4 | 4 | 2.9 | CC[C@H](/C=C/C=C\C[C@H](/C=C/C=C/C=C\[C@H](CCCC(=O)O)O)O)O | 10.1021/acs.jmedchem.3c01011 | ||
| DB13105 | 3319 | None | 18 | Human | Binding | pEC50 | = | 9 | 9.0 | - | 1 | Antagonist activity at human CMKLR1Antagonist activity at human CMKLR1 |
ChEMBL | 350 | 13 | 4 | 4 | 2.9 | CC[C@H](/C=C/C=C\C[C@H](/C=C/C=C/C=C\[C@H](CCCC(=O)O)O)O)O | 10.1021/acs.jmedchem.3c01011 | ||
| 162649940 | 180101 | None | 0 | Human | Binding | pIC50 | = | 6.6 | 6.6 | - | 0 | Inhibition of chemR23 expressed in human CAL1 cells assessed as reduction in chemerin-induced chemotaxis incubated for 4 hrs by cell counting based CellTiter-Glo assayInhibition of chemR23 expressed in human CAL1 cells assessed as reduction in chemerin-induced chemotaxis incubated for 4 hrs by cell counting based CellTiter-Glo assay |
ChEMBL | 532 | 9 | 2 | 7 | 6.6 | CCCCN(c1nc2c(C(=O)O)cccc2o1)[C@H](C)c1ccc(-c2cc(Cl)ccc2-c2nc(=O)o[nH]2)cc1 | 10.1016/j.bmc.2020.115622 | ||
| CHEMBL4746987 | 180101 | None | 0 | Human | Binding | pIC50 | = | 6.6 | 6.6 | - | 0 | Inhibition of chemR23 expressed in human CAL1 cells assessed as reduction in chemerin-induced chemotaxis incubated for 4 hrs by cell counting based CellTiter-Glo assayInhibition of chemR23 expressed in human CAL1 cells assessed as reduction in chemerin-induced chemotaxis incubated for 4 hrs by cell counting based CellTiter-Glo assay |
ChEMBL | 532 | 9 | 2 | 7 | 6.6 | CCCCN(c1nc2c(C(=O)O)cccc2o1)[C@H](C)c1ccc(-c2cc(Cl)ccc2-c2nc(=O)o[nH]2)cc1 | 10.1016/j.bmc.2020.115622 | ||
| 1518 | 368 | None | 2 | Human | Binding | pIC50 | = | 6.4 | 6.4 | - | 0 | Antagonist activity at human CMKLR1Antagonist activity at human CMKLR1 |
ChEMBL | 242 | 4 | 0 | 1 | 3.1 | O=C(c1cccc2c1cccc2)CC[N+](C)(C)C | 10.1021/acs.jmedchem.3c01011 | ||
| 9781 | 368 | None | 2 | Human | Binding | pIC50 | = | 6.4 | 6.4 | - | 0 | Antagonist activity at human CMKLR1Antagonist activity at human CMKLR1 |
ChEMBL | 242 | 4 | 0 | 1 | 3.1 | O=C(c1cccc2c1cccc2)CC[N+](C)(C)C | 10.1021/acs.jmedchem.3c01011 | ||
| CHEMBL1358898 | 368 | None | 2 | Human | Binding | pIC50 | = | 6.4 | 6.4 | - | 0 | Antagonist activity at human CMKLR1Antagonist activity at human CMKLR1 |
ChEMBL | 242 | 4 | 0 | 1 | 3.1 | O=C(c1cccc2c1cccc2)CC[N+](C)(C)C | 10.1021/acs.jmedchem.3c01011 | ||
| 155519352 | 170544 | None | 6 | Human | Binding | pIC50 | = | 6.4 | 6.4 | - | 0 | Inhibition of chemR23 expressed in human CAL1 cells assessed as reduction in chemerin-induced chemotaxis incubated for 4 hrs by cell counting based CellTiter-Glo assayInhibition of chemR23 expressed in human CAL1 cells assessed as reduction in chemerin-induced chemotaxis incubated for 4 hrs by cell counting based CellTiter-Glo assay |
ChEMBL | 495 | 9 | 2 | 7 | 5.4 | CCCCN(c1nc2cc(C(=O)NC)ccc2o1)[C@H](C)c1ccc(-c2ccccc2-c2nnn[nH]2)cc1 | 10.1016/j.bmc.2019.115091 | ||
| CHEMBL4448632 | 170544 | None | 6 | Human | Binding | pIC50 | = | 6.4 | 6.4 | - | 0 | Inhibition of chemR23 expressed in human CAL1 cells assessed as reduction in chemerin-induced chemotaxis incubated for 4 hrs by cell counting based CellTiter-Glo assayInhibition of chemR23 expressed in human CAL1 cells assessed as reduction in chemerin-induced chemotaxis incubated for 4 hrs by cell counting based CellTiter-Glo assay |
ChEMBL | 495 | 9 | 2 | 7 | 5.4 | CCCCN(c1nc2cc(C(=O)NC)ccc2o1)[C@H](C)c1ccc(-c2ccccc2-c2nnn[nH]2)cc1 | 10.1016/j.bmc.2019.115091 | ||
| 172443231 | 195106 | None | 0 | Human | Binding | pIC50 | = | 5.2 | 5.2 | - | 0 | Antagonist activity at human CMKLR1Antagonist activity at human CMKLR1 |
ChEMBL | 428 | 8 | 1 | 4 | 6.4 | CC(C)n1nc(-c2ccccc2)c2ccc(COc3ccc([C@@H](C)CC(=O)O)cc3)cc21 | 10.1021/acs.jmedchem.3c01011 | ||
| CHEMBL5396770 | 195106 | None | 0 | Human | Binding | pIC50 | = | 5.2 | 5.2 | - | 0 | Antagonist activity at human CMKLR1Antagonist activity at human CMKLR1 |
ChEMBL | 428 | 8 | 1 | 4 | 6.4 | CC(C)n1nc(-c2ccccc2)c2ccc(COc3ccc([C@@H](C)CC(=O)O)cc3)cc21 | 10.1021/acs.jmedchem.3c01011 | ||
| 162641724 | 182363 | None | 6 | Human | Binding | pIC50 | = | 7.2 | 7.2 | - | 0 | Inhibition of chemR23 expressed in human CAL1 cells assessed as reduction in chemerin-induced chemotaxis incubated for 4 hrs by cell counting based CellTiter-Glo assayInhibition of chemR23 expressed in human CAL1 cells assessed as reduction in chemerin-induced chemotaxis incubated for 4 hrs by cell counting based CellTiter-Glo assay |
ChEMBL | 510 | 8 | 2 | 7 | 5.8 | Cc1ccc(-c2nc(=O)o[nH]2)c(-c2ccc([C@@H](C)N(CC3CC3)c3nc4c(C(=O)O)cccc4o3)cc2)c1 | 10.1016/j.bmc.2020.115622 | ||
| CHEMBL4783675 | 182363 | None | 6 | Human | Binding | pIC50 | = | 7.2 | 7.2 | - | 0 | Inhibition of chemR23 expressed in human CAL1 cells assessed as reduction in chemerin-induced chemotaxis incubated for 4 hrs by cell counting based CellTiter-Glo assayInhibition of chemR23 expressed in human CAL1 cells assessed as reduction in chemerin-induced chemotaxis incubated for 4 hrs by cell counting based CellTiter-Glo assay |
ChEMBL | 510 | 8 | 2 | 7 | 5.8 | Cc1ccc(-c2nc(=O)o[nH]2)c(-c2ccc([C@@H](C)N(CC3CC3)c3nc4c(C(=O)O)cccc4o3)cc2)c1 | 10.1016/j.bmc.2020.115622 | ||
| 51034785 | 150885 | None | 0 | Human | Binding | pIC50 | = | 5.1 | 5.1 | - | 0 | Antagonist activity at human CMKLR1Antagonist activity at human CMKLR1 |
ChEMBL | 486 | 4 | 1 | 2 | 6.4 | Cc1cccc(C)c1N1C[C@](C(=O)Nc2cc(C(F)(F)F)cc(C(F)(F)F)c2)(C(C)C)CC1=O | 10.1021/acs.jmedchem.3c01011 | ||
| CHEMBL3956726 | 150885 | None | 0 | Human | Binding | pIC50 | = | 5.1 | 5.1 | - | 0 | Antagonist activity at human CMKLR1Antagonist activity at human CMKLR1 |
ChEMBL | 486 | 4 | 1 | 2 | 6.4 | Cc1cccc(C)c1N1C[C@](C(=O)Nc2cc(C(F)(F)F)cc(C(F)(F)F)c2)(C(C)C)CC1=O | 10.1021/acs.jmedchem.3c01011 | ||
| 9784 | 3787 | None | 0 | Human | Binding | pIC50 | ~ | 8.3 | 8.3 | - | 0 | Binding affinity in a radioligand displacement assay using membranes prepared from chemerinR-expressing CHO-K1 cells and <sup>125</sup>I-YHSFFFPGQFAFS as tracer.Binding affinity in a radioligand displacement assay using membranes prepared from chemerinR-expressing CHO-K1 cells and <sup>125</sup>I-YHSFFFPGQFAFS as tracer. |
Guide to Pharmacology | None | None | None | None | 14530373 | ||||
| 9784 | 3787 | None | 0 | Human | Binding | pIC50 | ~ | 8.3 | 8.3 | - | 0 | Binding affinity in a radioligand displacement assay using membranes prepared from chemerinR-expressing CHO-K1 cells and <sup>125</sup>I-YHSFFFPGQFAFS as tracer.Binding affinity in a radioligand displacement assay using membranes prepared from chemerinR-expressing CHO-K1 cells and <sup>125</sup>I-YHSFFFPGQFAFS as tracer. |
Guide to Pharmacology | None | None | None | None | 24659779 | ||||
| 11332190 | 909 | None | 15 | Human | Binding | pKd | = | 7.9 | 7.9 | - | 1 | UnclassifiedUnclassified |
Guide to Pharmacology | None | None | None | None | 14701797 | ||||
| 11332190 | 909 | None | 15 | Human | Binding | pKd | = | 7.9 | 7.9 | - | 1 | UnclassifiedUnclassified |
Guide to Pharmacology | None | None | None | None | 18165312 | ||||
| 156598973 | 909 | None | 15 | Human | Binding | pKd | = | 7.9 | 7.9 | - | 1 | UnclassifiedUnclassified |
Guide to Pharmacology | None | None | None | None | 14701797 | ||||
| 156598973 | 909 | None | 15 | Human | Binding | pKd | = | 7.9 | 7.9 | - | 1 | UnclassifiedUnclassified |
Guide to Pharmacology | None | None | None | None | 18165312 | ||||
| 3422 | 909 | None | 15 | Human | Binding | pKd | = | 7.9 | 7.9 | - | 1 | UnclassifiedUnclassified |
Guide to Pharmacology | None | None | None | None | 14701797 | ||||
| 3422 | 909 | None | 15 | Human | Binding | pKd | = | 7.9 | 7.9 | - | 1 | UnclassifiedUnclassified |
Guide to Pharmacology | None | None | None | None | 18165312 | ||||
| CHEMBL5081975 | 909 | None | 15 | Human | Binding | pKd | = | 7.9 | 7.9 | - | 1 | UnclassifiedUnclassified |
Guide to Pharmacology | None | None | None | None | 14701797 | ||||
| CHEMBL5081975 | 909 | None | 15 | Human | Binding | pKd | = | 7.9 | 7.9 | - | 1 | UnclassifiedUnclassified |
Guide to Pharmacology | None | None | None | None | 18165312 | ||||
| 10473088 | 3319 | None | 18 | Human | Binding | pKd | = | 8.0 | 8.0 | - | 1 | UnclassifiedUnclassified |
Guide to Pharmacology | 350 | 13 | 4 | 4 | 2.9 | CC[C@H](/C=C/C=C\C[C@H](/C=C/C=C/C=C\[C@H](CCCC(=O)O)O)O)O | 15753205 | ||
| 10473088 | 3319 | None | 18 | Human | Binding | pKd | = | 8.0 | 8.0 | - | 1 | UnclassifiedUnclassified |
Guide to Pharmacology | 350 | 13 | 4 | 4 | 2.9 | CC[C@H](/C=C/C=C\C[C@H](/C=C/C=C/C=C\[C@H](CCCC(=O)O)O)O)O | 17339491 | ||
| 10473088 | 3319 | None | 18 | Human | Binding | pKd | = | 8.0 | 8.0 | - | 1 | UnclassifiedUnclassified |
Guide to Pharmacology | 350 | 13 | 4 | 4 | 2.9 | CC[C@H](/C=C/C=C\C[C@H](/C=C/C=C/C=C\[C@H](CCCC(=O)O)O)O)O | 20887750 | ||
| 3333 | 3319 | None | 18 | Human | Binding | pKd | = | 8.0 | 8.0 | - | 1 | UnclassifiedUnclassified |
Guide to Pharmacology | 350 | 13 | 4 | 4 | 2.9 | CC[C@H](/C=C/C=C\C[C@H](/C=C/C=C/C=C\[C@H](CCCC(=O)O)O)O)O | 15753205 | ||
| 3333 | 3319 | None | 18 | Human | Binding | pKd | = | 8.0 | 8.0 | - | 1 | UnclassifiedUnclassified |
Guide to Pharmacology | 350 | 13 | 4 | 4 | 2.9 | CC[C@H](/C=C/C=C\C[C@H](/C=C/C=C/C=C\[C@H](CCCC(=O)O)O)O)O | 17339491 | ||
| 3333 | 3319 | None | 18 | Human | Binding | pKd | = | 8.0 | 8.0 | - | 1 | UnclassifiedUnclassified |
Guide to Pharmacology | 350 | 13 | 4 | 4 | 2.9 | CC[C@H](/C=C/C=C\C[C@H](/C=C/C=C/C=C\[C@H](CCCC(=O)O)O)O)O | 20887750 | ||
| CHEMBL1742483 | 3319 | None | 18 | Human | Binding | pKd | = | 8.0 | 8.0 | - | 1 | UnclassifiedUnclassified |
Guide to Pharmacology | 350 | 13 | 4 | 4 | 2.9 | CC[C@H](/C=C/C=C\C[C@H](/C=C/C=C/C=C\[C@H](CCCC(=O)O)O)O)O | 15753205 | ||
| CHEMBL1742483 | 3319 | None | 18 | Human | Binding | pKd | = | 8.0 | 8.0 | - | 1 | UnclassifiedUnclassified |
Guide to Pharmacology | 350 | 13 | 4 | 4 | 2.9 | CC[C@H](/C=C/C=C\C[C@H](/C=C/C=C/C=C\[C@H](CCCC(=O)O)O)O)O | 17339491 | ||
| CHEMBL1742483 | 3319 | None | 18 | Human | Binding | pKd | = | 8.0 | 8.0 | - | 1 | UnclassifiedUnclassified |
Guide to Pharmacology | 350 | 13 | 4 | 4 | 2.9 | CC[C@H](/C=C/C=C\C[C@H](/C=C/C=C/C=C\[C@H](CCCC(=O)O)O)O)O | 20887750 | ||
| DB13105 | 3319 | None | 18 | Human | Binding | pKd | = | 8.0 | 8.0 | - | 1 | UnclassifiedUnclassified |
Guide to Pharmacology | 350 | 13 | 4 | 4 | 2.9 | CC[C@H](/C=C/C=C\C[C@H](/C=C/C=C/C=C\[C@H](CCCC(=O)O)O)O)O | 15753205 | ||
| DB13105 | 3319 | None | 18 | Human | Binding | pKd | = | 8.0 | 8.0 | - | 1 | UnclassifiedUnclassified |
Guide to Pharmacology | 350 | 13 | 4 | 4 | 2.9 | CC[C@H](/C=C/C=C\C[C@H](/C=C/C=C/C=C\[C@H](CCCC(=O)O)O)O)O | 17339491 | ||
| DB13105 | 3319 | None | 18 | Human | Binding | pKd | = | 8.0 | 8.0 | - | 1 | UnclassifiedUnclassified |
Guide to Pharmacology | 350 | 13 | 4 | 4 | 2.9 | CC[C@H](/C=C/C=C\C[C@H](/C=C/C=C/C=C\[C@H](CCCC(=O)O)O)O)O | 20887750 | ||
| 2945 | 908 | None | 0 | Human | Binding | pKd | = | 8.3 | 8.3 | 1 | 2 | UnclassifiedUnclassified |
Guide to Pharmacology | None | None | None | None | 18165312 | ||||
Showing 1 to 40 of 40 entries