Ligand source activities (1 row/activity)
| Ligands (move mouse cursor over ligand name to see structure) | Receptor | Activity | Chemical information | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Sel. page | Common name
| GPCRdb ID
| Reference ligand
| Vendors | Species
| Assay Type
| Activity Type
| Activity Relation
| Activity Value | p-value (-log) | Fold selectivity | Tested GPCRs | Assay Description
| Source
| Mol weight | Rot Bonds | H don | H acc | LogP | Smiles
| DOI
| |
Ligands (move mouse cursor over ligand name to see structure)
| Receptor
| Activity
| Chemical information
| |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sel. page | Common name
| GPCRdb ID
| Reference ligand
| Vendors | Species
| Assay Type
| Activity Type
| Activity Relation
| Activity Value | p-value (-log) | Fold selectivity | Tested GPCRs | Assay Description
| Source
| Mol weight | Rot Bonds | H don | H acc | LogP | Smiles
| DOI
| |
| 5311263 | 4157 | None | 20 | Mouse | Functional | pEC50 | = | 6.6 | 6.6 | -36 | 7 | Agonist activity at mouse LPA4 expressed in CHO cells by Fura-2AM dye based Ca2+ mobilization assayAgonist activity at mouse LPA4 expressed in CHO cells by Fura-2AM dye based Ca2+ mobilization assay |
ChEMBL | 436 | 20 | 3 | 5 | 5.0 | CCCCCCCC/C=C\CCCCCCCC(=O)OC[C@@H](O)COP(=O)(O)O | 10.1021/jm5007116 | ||
| CHEMBL117021 | 4157 | None | 20 | Mouse | Functional | pEC50 | = | 6.6 | 6.6 | -36 | 7 | Agonist activity at mouse LPA4 expressed in CHO cells by Fura-2AM dye based Ca2+ mobilization assayAgonist activity at mouse LPA4 expressed in CHO cells by Fura-2AM dye based Ca2+ mobilization assay |
ChEMBL | 436 | 20 | 3 | 5 | 5.0 | CCCCCCCC/C=C\CCCCCCCC(=O)OC[C@@H](O)COP(=O)(O)O | 10.1021/jm5007116 | ||
| 2906 | 2355 | None | 15 | Human | Functional | pEC50 | = | 6.2 | 6.2 | -72 | 12 | Agonist activity at LPA4 receptor (unknown origin) expressed in CHO cells assessed as increase in intracellular calcium level measured every 3.42 secs for 70 secs by Fura-2-AM dye based fluorescence assayAgonist activity at LPA4 receptor (unknown origin) expressed in CHO cells assessed as increase in intracellular calcium level measured every 3.42 secs for 70 secs by Fura-2-AM dye based fluorescence assay |
ChEMBL | 436 | 20 | 3 | 5 | 5.0 | CCCCCCCC/C=C\CCCCCCCC(=O)OCC(COP(=O)(O)O)O | 10.1021/acs.jmedchem.6b01270 | ||
| 5395 | 2355 | None | 15 | Human | Functional | pEC50 | = | 6.2 | 6.2 | -72 | 12 | Agonist activity at LPA4 receptor (unknown origin) expressed in CHO cells assessed as increase in intracellular calcium level measured every 3.42 secs for 70 secs by Fura-2-AM dye based fluorescence assayAgonist activity at LPA4 receptor (unknown origin) expressed in CHO cells assessed as increase in intracellular calcium level measured every 3.42 secs for 70 secs by Fura-2-AM dye based fluorescence assay |
ChEMBL | 436 | 20 | 3 | 5 | 5.0 | CCCCCCCC/C=C\CCCCCCCC(=O)OCC(COP(=O)(O)O)O | 10.1021/acs.jmedchem.6b01270 | ||
| 5497152 | 2355 | None | 15 | Human | Functional | pEC50 | = | 6.2 | 6.2 | -72 | 12 | Agonist activity at LPA4 receptor (unknown origin) expressed in CHO cells assessed as increase in intracellular calcium level measured every 3.42 secs for 70 secs by Fura-2-AM dye based fluorescence assayAgonist activity at LPA4 receptor (unknown origin) expressed in CHO cells assessed as increase in intracellular calcium level measured every 3.42 secs for 70 secs by Fura-2-AM dye based fluorescence assay |
ChEMBL | 436 | 20 | 3 | 5 | 5.0 | CCCCCCCC/C=C\CCCCCCCC(=O)OCC(COP(=O)(O)O)O | 10.1021/acs.jmedchem.6b01270 | ||
| CHEMBL1222042 | 2355 | None | 15 | Human | Functional | pEC50 | = | 6.2 | 6.2 | -72 | 12 | Agonist activity at LPA4 receptor (unknown origin) expressed in CHO cells assessed as increase in intracellular calcium level measured every 3.42 secs for 70 secs by Fura-2-AM dye based fluorescence assayAgonist activity at LPA4 receptor (unknown origin) expressed in CHO cells assessed as increase in intracellular calcium level measured every 3.42 secs for 70 secs by Fura-2-AM dye based fluorescence assay |
ChEMBL | 436 | 20 | 3 | 5 | 5.0 | CCCCCCCC/C=C\CCCCCCCC(=O)OCC(COP(=O)(O)O)O | 10.1021/acs.jmedchem.6b01270 | ||
| 164579607 | 196466 | None | 0 | Human | Functional | pIC50 | = | 4.6 | 4.6 | -50 | 3 | Antagonist activity at human LPA4 receptor expressed in CHO cells assessed as inhibition of LPA-induced cAMP accumulation pretreated for 30 mins followed by LPA stimulation and measured after 1 hrAntagonist activity at human LPA4 receptor expressed in CHO cells assessed as inhibition of LPA-induced cAMP accumulation pretreated for 30 mins followed by LPA stimulation and measured after 1 hr |
ChEMBL | 525 | 7 | 2 | 11 | 2.8 | COC(=O)Nc1nc(C)c(S(=O)(=O)N2CCN(C[C@H](C)Nc3ncnc4c(C)csc34)CC2)s1 | 10.1021/acs.jmedchem.2c02087 | ||
| CHEMBL5424552 | 196466 | None | 0 | Human | Functional | pIC50 | = | 4.6 | 4.6 | -50 | 3 | Antagonist activity at human LPA4 receptor expressed in CHO cells assessed as inhibition of LPA-induced cAMP accumulation pretreated for 30 mins followed by LPA stimulation and measured after 1 hrAntagonist activity at human LPA4 receptor expressed in CHO cells assessed as inhibition of LPA-induced cAMP accumulation pretreated for 30 mins followed by LPA stimulation and measured after 1 hr |
ChEMBL | 525 | 7 | 2 | 11 | 2.8 | COC(=O)Nc1nc(C)c(S(=O)(=O)N2CCN(C[C@H](C)Nc3ncnc4c(C)csc34)CC2)s1 | 10.1021/acs.jmedchem.2c02087 | ||
| 122191544 | 123770 | None | 0 | Human | Functional | pIC50 | = | 6.6 | 6.6 | 4 | 4 | Antagonist activity at human LPA4 receptor expressed in CHO cells assessed as inhibition of LPA-induced calcium mobilization by Fura-2 AM probe-based fluorometric analysisAntagonist activity at human LPA4 receptor expressed in CHO cells assessed as inhibition of LPA-induced calcium mobilization by Fura-2 AM probe-based fluorometric analysis |
ChEMBL | 484 | 18 | 3 | 4 | 5.4 | CCCCCC/C=C\CCCCCCCC(=O)OC[C@@H](O)CC(Br)P(=O)(O)O | 10.1039/C4MD00333K | ||
| CHEMBL3621964 | 123770 | None | 0 | Human | Functional | pIC50 | = | 6.6 | 6.6 | 4 | 4 | Antagonist activity at human LPA4 receptor expressed in CHO cells assessed as inhibition of LPA-induced calcium mobilization by Fura-2 AM probe-based fluorometric analysisAntagonist activity at human LPA4 receptor expressed in CHO cells assessed as inhibition of LPA-induced calcium mobilization by Fura-2 AM probe-based fluorometric analysis |
ChEMBL | 484 | 18 | 3 | 4 | 5.4 | CCCCCC/C=C\CCCCCCCC(=O)OC[C@@H](O)CC(Br)P(=O)(O)O | 10.1039/C4MD00333K | ||
| 24882686 | 95359 | None | 35 | Human | Functional | pIC50 | = | 5.2 | 5.2 | -58 | 6 | Antagonist activity at human LPA4 receptor expressed in CHO cells assessed as inhibition of LPA-induced cAMP accumulation pretreated for 30 mins followed by LPA stimulation and measured after 1 hrAntagonist activity at human LPA4 receptor expressed in CHO cells assessed as inhibition of LPA-induced cAMP accumulation pretreated for 30 mins followed by LPA stimulation and measured after 1 hr |
ChEMBL | 499 | 6 | 1 | 7 | 4.1 | Cc1csc2c(N[C@@H](C)CN3CCN(S(=O)(=O)c4ccc(Cl)c(Cl)c4)CC3)ncnc12 | 10.1021/acs.jmedchem.2c02087 | ||
| CHEMBL256470 | 95359 | None | 35 | Human | Functional | pIC50 | = | 5.2 | 5.2 | -58 | 6 | Antagonist activity at human LPA4 receptor expressed in CHO cells assessed as inhibition of LPA-induced cAMP accumulation pretreated for 30 mins followed by LPA stimulation and measured after 1 hrAntagonist activity at human LPA4 receptor expressed in CHO cells assessed as inhibition of LPA-induced cAMP accumulation pretreated for 30 mins followed by LPA stimulation and measured after 1 hr |
ChEMBL | 499 | 6 | 1 | 7 | 4.1 | Cc1csc2c(N[C@@H](C)CN3CCN(S(=O)(=O)c4ccc(Cl)c(Cl)c4)CC3)ncnc12 | 10.1021/acs.jmedchem.2c02087 | ||
| 16725999 | 731 | None | 2 | Human | Functional | pKi | = | 6.8 | 6.8 | - | 2 | Antagonist activity at human LPA4 receptor expressed in CHO cells assessed as inhibition of LPA-induced Ca2+ mobilization by FURA-2AM dye based fluorescence assayAntagonist activity at human LPA4 receptor expressed in CHO cells assessed as inhibition of LPA-induced Ca2+ mobilization by FURA-2AM dye based fluorescence assay |
ChEMBL | 486 | 19 | 3 | 4 | 5.7 | CCCCCCCCCCCCCCCC(=O)OC[C@H](CC(P(=O)(O)O)Br)O | 10.1039/C4MD00255E | ||
| 6985 | 731 | None | 2 | Human | Functional | pKi | = | 6.8 | 6.8 | - | 2 | Antagonist activity at human LPA4 receptor expressed in CHO cells assessed as inhibition of LPA-induced Ca2+ mobilization by FURA-2AM dye based fluorescence assayAntagonist activity at human LPA4 receptor expressed in CHO cells assessed as inhibition of LPA-induced Ca2+ mobilization by FURA-2AM dye based fluorescence assay |
ChEMBL | 486 | 19 | 3 | 4 | 5.7 | CCCCCCCCCCCCCCCC(=O)OC[C@H](CC(P(=O)(O)O)Br)O | 10.1039/C4MD00255E | ||
| CHEMBL3621357 | 731 | None | 2 | Human | Functional | pKi | = | 6.8 | 6.8 | - | 2 | Antagonist activity at human LPA4 receptor expressed in CHO cells assessed as inhibition of LPA-induced Ca2+ mobilization by FURA-2AM dye based fluorescence assayAntagonist activity at human LPA4 receptor expressed in CHO cells assessed as inhibition of LPA-induced Ca2+ mobilization by FURA-2AM dye based fluorescence assay |
ChEMBL | 486 | 19 | 3 | 4 | 5.7 | CCCCCCCCCCCCCCCC(=O)OC[C@H](CC(P(=O)(O)O)Br)O | 10.1039/C4MD00255E | ||
| 87470750 | 123884 | None | 0 | Human | Functional | pKi | = | 6.8 | 6.8 | - | 0 | Antagonist activity at human LPA4 receptor expressed in CHO cells assessed as inhibition of LPA-induced Ca2+ mobilization by FURA-2AM dye based fluorescence assayAntagonist activity at human LPA4 receptor expressed in CHO cells assessed as inhibition of LPA-induced Ca2+ mobilization by FURA-2AM dye based fluorescence assay |
ChEMBL | 512 | 20 | 3 | 4 | 6.2 | CCCCCCCC/C=C\CCCCCCCC(=O)OC[C@@H](O)CC(Br)P(=O)(O)O | 10.1039/C4MD00255E | ||
| CHEMBL3621353 | 123884 | None | 0 | Human | Functional | pKi | = | 6.8 | 6.8 | - | 0 | Antagonist activity at human LPA4 receptor expressed in CHO cells assessed as inhibition of LPA-induced Ca2+ mobilization by FURA-2AM dye based fluorescence assayAntagonist activity at human LPA4 receptor expressed in CHO cells assessed as inhibition of LPA-induced Ca2+ mobilization by FURA-2AM dye based fluorescence assay |
ChEMBL | 512 | 20 | 3 | 4 | 6.2 | CCCCCCCC/C=C\CCCCCCCC(=O)OC[C@@H](O)CC(Br)P(=O)(O)O | 10.1039/C4MD00255E | ||
| CHEMBL3623936 | 123884 | None | 0 | Human | Functional | pKi | = | 6.8 | 6.8 | - | 0 | Antagonist activity at human LPA4 receptor expressed in CHO cells assessed as inhibition of LPA-induced Ca2+ mobilization by FURA-2AM dye based fluorescence assayAntagonist activity at human LPA4 receptor expressed in CHO cells assessed as inhibition of LPA-induced Ca2+ mobilization by FURA-2AM dye based fluorescence assay |
ChEMBL | 512 | 20 | 3 | 4 | 6.2 | CCCCCCCC/C=C\CCCCCCCC(=O)OC[C@@H](O)CC(Br)P(=O)(O)O | 10.1039/C4MD00255E | ||
| 23682233 | 31 | None | 0 | Human | Functional | pIC50 | = | 6.6 | 6.6 | - | 1 | UnclassifiedUnclassified |
Guide to Pharmacology | 508 | 20 | 2 | 5 | 5.8 | CCCCCCCCCCCCCCCC(=O)OC[C@H](CC(P(=O)(O[Na])O)Br)O | 18781939 | ||
| 6991 | 31 | None | 0 | Human | Functional | pIC50 | = | 6.6 | 6.6 | - | 1 | UnclassifiedUnclassified |
Guide to Pharmacology | 508 | 20 | 2 | 5 | 5.8 | CCCCCCCCCCCCCCCC(=O)OC[C@H](CC(P(=O)(O[Na])O)Br)O | 18781939 | ||
| CHEMBL3621354 | 31 | None | 0 | Human | Functional | pIC50 | = | 6.6 | 6.6 | - | 1 | UnclassifiedUnclassified |
Guide to Pharmacology | 508 | 20 | 2 | 5 | 5.8 | CCCCCCCCCCCCCCCC(=O)OC[C@H](CC(P(=O)(O[Na])O)Br)O | 18781939 | ||
| 2905 | 389 | None | 41 | Human | Functional | pIC50 | None | 5.1 | 5.1 | -398 | 7 | UnclassifiedUnclassified |
Guide to Pharmacology | 490 | 7 | 2 | 5 | 6.9 | OC(=O)Cc1ccc(cc1)c1ccc(cc1)c1onc(c1NC(=O)O[C@@H](c1ccccc1Cl)C)C | 20649573 | ||
| 46240292 | 389 | None | 41 | Human | Functional | pIC50 | None | 5.1 | 5.1 | -398 | 7 | UnclassifiedUnclassified |
Guide to Pharmacology | 490 | 7 | 2 | 5 | 6.9 | OC(=O)Cc1ccc(cc1)c1ccc(cc1)c1onc(c1NC(=O)O[C@@H](c1ccccc1Cl)C)C | 20649573 | ||
| CHEMBL3621966 | 389 | None | 41 | Human | Functional | pIC50 | None | 5.1 | 5.1 | -398 | 7 | UnclassifiedUnclassified |
Guide to Pharmacology | 490 | 7 | 2 | 5 | 6.9 | OC(=O)Cc1ccc(cc1)c1ccc(cc1)c1onc(c1NC(=O)O[C@@H](c1ccccc1Cl)C)C | 20649573 | ||
| 11132720 | 1622 | None | 0 | Human | Functional | pIC50 | None | 5.7 | 5.7 | -12 | 4 | UnclassifiedUnclassified |
Guide to Pharmacology | 382 | 11 | 3 | 4 | 4.6 | C/C(=C/COP(=O)(OP(=O)(O)O)O)/CC/C=C(\CCC=C(C)C)/C | 19366702 | ||
| 2910 | 1622 | None | 0 | Human | Functional | pIC50 | None | 5.7 | 5.7 | -12 | 4 | UnclassifiedUnclassified |
Guide to Pharmacology | 382 | 11 | 3 | 4 | 4.6 | C/C(=C/COP(=O)(OP(=O)(O)O)O)/CC/C=C(\CCC=C(C)C)/C | 19366702 | ||
| DB07780 | 1622 | None | 0 | Human | Functional | pIC50 | None | 5.7 | 5.7 | -12 | 4 | UnclassifiedUnclassified |
Guide to Pharmacology | 382 | 11 | 3 | 4 | 4.6 | C/C(=C/COP(=O)(OP(=O)(O)O)O)/CC/C=C(\CCC=C(C)C)/C | 19366702 | ||
| 2911 | 1623 | None | 0 | Human | Functional | pIC50 | None | 5.8 | 5.8 | -29 | 4 | UnclassifiedUnclassified |
Guide to Pharmacology | 302 | 9 | 2 | 2 | 4.5 | C/C(=C/CC/C(=C\COP(=O)(O)O)/C)/CCC=C(C)C | 19366702 | ||
| 6440220 | 1623 | None | 0 | Human | Functional | pIC50 | None | 5.8 | 5.8 | -29 | 4 | UnclassifiedUnclassified |
Guide to Pharmacology | 302 | 9 | 2 | 2 | 4.5 | C/C(=C/CC/C(=C\COP(=O)(O)O)/C)/CCC=C(C)C | 19366702 | ||
Showing 1 to 29 of 29 entries
| Ligands (move mouse cursor over ligand name to see structure) | Receptor | Activity | Chemical information | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Sel. page | Common name
| GPCRdb ID
| Reference ligand
| Vendors | Species
| Assay Type
| Activity Type
| Activity Relation
| Activity Value | p-value (-log) | Fold selectivity | Tested GPCRs | Assay Description
| Source
| Mol weight | Rot Bonds | H don | H acc | LogP | Smiles
| DOI
| |
Ligands (move mouse cursor over ligand name to see structure)
| Receptor
| Activity
| Chemical information
| |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sel. page | Common name
| GPCRdb ID
| Reference ligand
| Vendors | Species
| Assay Type
| Activity Type
| Activity Relation
| Activity Value | p-value (-log) | Fold selectivity | Tested GPCRs | Assay Description
| Source
| Mol weight | Rot Bonds | H don | H acc | LogP | Smiles
| DOI
| |
| 11496444 | 89093 | None | 0 | Human | Binding | pEC50 | = | 8.6 | 8.6 | - | 0 | Agonist activity at human LPA4 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay in presence of Ki16425Agonist activity at human LPA4 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay in presence of Ki16425 |
ChEMBL | 468 | 22 | 2 | 5 | 6.0 | CCCCCCCCCCCCCCCCCC(=O)OC(COC)COP(O)(O)=S | 10.1016/j.bmcl.2013.01.002 | ||
| CHEMBL2335051 | 89093 | None | 0 | Human | Binding | pEC50 | = | 8.6 | 8.6 | - | 0 | Agonist activity at human LPA4 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay in presence of Ki16425Agonist activity at human LPA4 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay in presence of Ki16425 |
ChEMBL | 468 | 22 | 2 | 5 | 6.0 | CCCCCCCCCCCCCCCCCC(=O)OC(COC)COP(O)(O)=S | 10.1016/j.bmcl.2013.01.002 | ||
| CHEMBL2364959 | 89093 | None | 0 | Human | Binding | pEC50 | = | 8.6 | 8.6 | - | 0 | Agonist activity at human LPA4 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay in presence of Ki16425Agonist activity at human LPA4 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay in presence of Ki16425 |
ChEMBL | 468 | 22 | 2 | 5 | 6.0 | CCCCCCCCCCCCCCCCCC(=O)OC(COC)COP(O)(O)=S | 10.1016/j.bmcl.2013.01.002 | ||
| 11496444 | 89093 | None | 0 | Human | Binding | pEC50 | = | 8.6 | 8.6 | - | 0 | Agonist activity at human LPA4 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay in presence of Ki16425Agonist activity at human LPA4 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay in presence of Ki16425 |
ChEMBL | 468 | 22 | 2 | 5 | 6.0 | CCCCCCCCCCCCCCCCCC(=O)OC(COC)COP(O)(O)=S | 10.1016/j.bmcl.2013.01.002 | ||
| CHEMBL2335051 | 89093 | None | 0 | Human | Binding | pEC50 | = | 8.6 | 8.6 | - | 0 | Agonist activity at human LPA4 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay in presence of Ki16425Agonist activity at human LPA4 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay in presence of Ki16425 |
ChEMBL | 468 | 22 | 2 | 5 | 6.0 | CCCCCCCCCCCCCCCCCC(=O)OC(COC)COP(O)(O)=S | 10.1016/j.bmcl.2013.01.002 | ||
| CHEMBL2364959 | 89093 | None | 0 | Human | Binding | pEC50 | = | 8.6 | 8.6 | - | 0 | Agonist activity at human LPA4 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay in presence of Ki16425Agonist activity at human LPA4 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay in presence of Ki16425 |
ChEMBL | 468 | 22 | 2 | 5 | 6.0 | CCCCCCCCCCCCCCCCCC(=O)OC(COC)COP(O)(O)=S | 10.1016/j.bmcl.2013.01.002 | ||
| 10322404 | 121145 | None | 0 | Human | Binding | pEC50 | = | 8.6 | 8.6 | - | 0 | Agonist activity at human LPA4 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay in presence of Ki16425Agonist activity at human LPA4 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay in presence of Ki16425 |
ChEMBL | 468 | 22 | 2 | 5 | 6.0 | CCCCCCCCCCCCCCCCCC(=O)OC[C@@H](COP(O)(O)=S)OC | 10.1016/j.bmcl.2013.01.002 | ||
| CHEMBL357053 | 121145 | None | 0 | Human | Binding | pEC50 | = | 8.6 | 8.6 | - | 0 | Agonist activity at human LPA4 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay in presence of Ki16425Agonist activity at human LPA4 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay in presence of Ki16425 |
ChEMBL | 468 | 22 | 2 | 5 | 6.0 | CCCCCCCCCCCCCCCCCC(=O)OC[C@@H](COP(O)(O)=S)OC | 10.1016/j.bmcl.2013.01.002 | ||
| 10322404 | 121145 | None | 0 | Human | Binding | pEC50 | = | 8.6 | 8.6 | - | 0 | Agonist activity at human LPA4 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay in presence of Ki16425Agonist activity at human LPA4 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay in presence of Ki16425 |
ChEMBL | 468 | 22 | 2 | 5 | 6.0 | CCCCCCCCCCCCCCCCCC(=O)OC[C@@H](COP(O)(O)=S)OC | 10.1016/j.bmcl.2013.01.002 | ||
| CHEMBL357053 | 121145 | None | 0 | Human | Binding | pEC50 | = | 8.6 | 8.6 | - | 0 | Agonist activity at human LPA4 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay in presence of Ki16425Agonist activity at human LPA4 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay in presence of Ki16425 |
ChEMBL | 468 | 22 | 2 | 5 | 6.0 | CCCCCCCCCCCCCCCCCC(=O)OC[C@@H](COP(O)(O)=S)OC | 10.1016/j.bmcl.2013.01.002 | ||
| CHEMBL5085657 | 217467 | None | 0 | Human | Binding | pEC50 | = | 5.7 | 5.7 | - | 0 | Activation of human GPR23 stably expressed in CHO cells expressing Galpha16Activation of human GPR23 stably expressed in CHO cells expressing Galpha16 |
ChEMBL | None | None | None | CC(C)C[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCCN)NC(=O)[C@@H](N)CCC(N)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H](C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@H](C(=O)O)C(C)C)C(C)C)C(C)C | nan | ||||
| 46223906 | 73546 | None | 0 | Human | Binding | pEC50 | = | 8.5 | 8.5 | - | 0 | Agonist activity at human LPA4 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay in presence of Ki16425Agonist activity at human LPA4 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay in presence of Ki16425 |
ChEMBL | 468 | 22 | 2 | 5 | 6.9 | CCCCCCCCCCCCCCCCCC(=O)OCC(COP(=O)(O)S)OC | 10.1016/j.bmcl.2013.01.002 | ||
| CHEMBL2017139 | 73546 | None | 0 | Human | Binding | pEC50 | = | 8.5 | 8.5 | - | 0 | Agonist activity at human LPA4 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay in presence of Ki16425Agonist activity at human LPA4 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay in presence of Ki16425 |
ChEMBL | 468 | 22 | 2 | 5 | 6.9 | CCCCCCCCCCCCCCCCCC(=O)OCC(COP(=O)(O)S)OC | 10.1016/j.bmcl.2013.01.002 | ||
| 46223906 | 73546 | None | 0 | Human | Binding | pEC50 | = | 8.5 | 8.5 | - | 0 | Agonist activity at human LPA4 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay in presence of Ki16425Agonist activity at human LPA4 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay in presence of Ki16425 |
ChEMBL | 468 | 22 | 2 | 5 | 6.9 | CCCCCCCCCCCCCCCCCC(=O)OCC(COP(=O)(O)S)OC | 10.1016/j.bmcl.2013.01.002 | ||
| CHEMBL2017139 | 73546 | None | 0 | Human | Binding | pEC50 | = | 8.5 | 8.5 | - | 0 | Agonist activity at human LPA4 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay in presence of Ki16425Agonist activity at human LPA4 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay in presence of Ki16425 |
ChEMBL | 468 | 22 | 2 | 5 | 6.9 | CCCCCCCCCCCCCCCCCC(=O)OCC(COP(=O)(O)S)OC | 10.1016/j.bmcl.2013.01.002 | ||
| 71720690 | 87558 | None | 0 | Human | Binding | pEC50 | = | 8.5 | 8.5 | - | 0 | Agonist activity at human LPA4 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay in presence of Ki16425Agonist activity at human LPA4 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay in presence of Ki16425 |
ChEMBL | 454 | 23 | 2 | 4 | 6.5 | CCCCCCCCCCCCCCCCCCOC[C@@H](COP(O)(O)=S)OC | 10.1016/j.bmcl.2013.01.002 | ||
| CHEMBL2335047 | 87558 | None | 0 | Human | Binding | pEC50 | = | 8.5 | 8.5 | - | 0 | Agonist activity at human LPA4 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay in presence of Ki16425Agonist activity at human LPA4 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay in presence of Ki16425 |
ChEMBL | 454 | 23 | 2 | 4 | 6.5 | CCCCCCCCCCCCCCCCCCOC[C@@H](COP(O)(O)=S)OC | 10.1016/j.bmcl.2013.01.002 | ||
| 71720690 | 87558 | None | 0 | Human | Binding | pEC50 | = | 8.5 | 8.5 | - | 0 | Agonist activity at human LPA4 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay in presence of Ki16425Agonist activity at human LPA4 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay in presence of Ki16425 |
ChEMBL | 454 | 23 | 2 | 4 | 6.5 | CCCCCCCCCCCCCCCCCCOC[C@@H](COP(O)(O)=S)OC | 10.1016/j.bmcl.2013.01.002 | ||
| CHEMBL2335047 | 87558 | None | 0 | Human | Binding | pEC50 | = | 8.5 | 8.5 | - | 0 | Agonist activity at human LPA4 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay in presence of Ki16425Agonist activity at human LPA4 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay in presence of Ki16425 |
ChEMBL | 454 | 23 | 2 | 4 | 6.5 | CCCCCCCCCCCCCCCCCCOC[C@@H](COP(O)(O)=S)OC | 10.1016/j.bmcl.2013.01.002 | ||
| 11648176 | 87560 | None | 0 | Human | Binding | pEC50 | = | 8.4 | 8.4 | - | 0 | Agonist activity at human LPA4 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay in presence of Ki16425Agonist activity at human LPA4 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay in presence of Ki16425 |
ChEMBL | 454 | 23 | 2 | 4 | 6.5 | CCCCCCCCCCCCCCCCCCOCC(COP(O)(O)=S)OC | 10.1016/j.bmcl.2013.01.002 | ||
| CHEMBL2335052 | 87560 | None | 0 | Human | Binding | pEC50 | = | 8.4 | 8.4 | - | 0 | Agonist activity at human LPA4 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay in presence of Ki16425Agonist activity at human LPA4 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay in presence of Ki16425 |
ChEMBL | 454 | 23 | 2 | 4 | 6.5 | CCCCCCCCCCCCCCCCCCOCC(COP(O)(O)=S)OC | 10.1016/j.bmcl.2013.01.002 | ||
| 71569054 | 89102 | None | 0 | Human | Binding | pEC50 | = | 8.4 | 8.4 | - | 0 | Agonist activity at human LPA4 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay in presence of Ki16425Agonist activity at human LPA4 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay in presence of Ki16425 |
ChEMBL | 426 | 21 | 2 | 4 | 5.7 | CCCCCCCCCCCCCCCCOC(COC)COP(O)(O)=S | 10.1016/j.bmcl.2013.01.002 | ||
| CHEMBL2335049 | 89102 | None | 0 | Human | Binding | pEC50 | = | 8.4 | 8.4 | - | 0 | Agonist activity at human LPA4 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay in presence of Ki16425Agonist activity at human LPA4 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay in presence of Ki16425 |
ChEMBL | 426 | 21 | 2 | 4 | 5.7 | CCCCCCCCCCCCCCCCOC(COC)COP(O)(O)=S | 10.1016/j.bmcl.2013.01.002 | ||
| CHEMBL2365070 | 89102 | None | 0 | Human | Binding | pEC50 | = | 8.4 | 8.4 | - | 0 | Agonist activity at human LPA4 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay in presence of Ki16425Agonist activity at human LPA4 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay in presence of Ki16425 |
ChEMBL | 426 | 21 | 2 | 4 | 5.7 | CCCCCCCCCCCCCCCCOC(COC)COP(O)(O)=S | 10.1016/j.bmcl.2013.01.002 | ||
| 11648176 | 87560 | None | 0 | Human | Binding | pEC50 | = | 8.4 | 8.4 | - | 0 | Agonist activity at human LPA4 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay in presence of Ki16425Agonist activity at human LPA4 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay in presence of Ki16425 |
ChEMBL | 454 | 23 | 2 | 4 | 6.5 | CCCCCCCCCCCCCCCCCCOCC(COP(O)(O)=S)OC | 10.1016/j.bmcl.2013.01.002 | ||
| CHEMBL2335052 | 87560 | None | 0 | Human | Binding | pEC50 | = | 8.4 | 8.4 | - | 0 | Agonist activity at human LPA4 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay in presence of Ki16425Agonist activity at human LPA4 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay in presence of Ki16425 |
ChEMBL | 454 | 23 | 2 | 4 | 6.5 | CCCCCCCCCCCCCCCCCCOCC(COP(O)(O)=S)OC | 10.1016/j.bmcl.2013.01.002 | ||
| 71569054 | 89102 | None | 0 | Human | Binding | pEC50 | = | 8.4 | 8.4 | - | 0 | Agonist activity at human LPA4 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay in presence of Ki16425Agonist activity at human LPA4 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay in presence of Ki16425 |
ChEMBL | 426 | 21 | 2 | 4 | 5.7 | CCCCCCCCCCCCCCCCOC(COC)COP(O)(O)=S | 10.1016/j.bmcl.2013.01.002 | ||
| CHEMBL2335049 | 89102 | None | 0 | Human | Binding | pEC50 | = | 8.4 | 8.4 | - | 0 | Agonist activity at human LPA4 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay in presence of Ki16425Agonist activity at human LPA4 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay in presence of Ki16425 |
ChEMBL | 426 | 21 | 2 | 4 | 5.7 | CCCCCCCCCCCCCCCCOC(COC)COP(O)(O)=S | 10.1016/j.bmcl.2013.01.002 | ||
| CHEMBL2365070 | 89102 | None | 0 | Human | Binding | pEC50 | = | 8.4 | 8.4 | - | 0 | Agonist activity at human LPA4 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay in presence of Ki16425Agonist activity at human LPA4 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay in presence of Ki16425 |
ChEMBL | 426 | 21 | 2 | 4 | 5.7 | CCCCCCCCCCCCCCCCOC(COC)COP(O)(O)=S | 10.1016/j.bmcl.2013.01.002 | ||
| 71599962 | 89103 | None | 0 | Human | Binding | pEC50 | = | 8.4 | 8.4 | - | 0 | Agonist activity at human LPA4 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay in presence of Ki16425Agonist activity at human LPA4 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay in presence of Ki16425 |
ChEMBL | 440 | 22 | 2 | 4 | 6.1 | CCCCCCCCCCCCCCCCCOC(COC)COP(O)(O)=S | 10.1016/j.bmcl.2013.01.002 | ||
| CHEMBL2335050 | 89103 | None | 0 | Human | Binding | pEC50 | = | 8.4 | 8.4 | - | 0 | Agonist activity at human LPA4 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay in presence of Ki16425Agonist activity at human LPA4 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay in presence of Ki16425 |
ChEMBL | 440 | 22 | 2 | 4 | 6.1 | CCCCCCCCCCCCCCCCCOC(COC)COP(O)(O)=S | 10.1016/j.bmcl.2013.01.002 | ||
| CHEMBL2365071 | 89103 | None | 0 | Human | Binding | pEC50 | = | 8.4 | 8.4 | - | 0 | Agonist activity at human LPA4 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay in presence of Ki16425Agonist activity at human LPA4 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay in presence of Ki16425 |
ChEMBL | 440 | 22 | 2 | 4 | 6.1 | CCCCCCCCCCCCCCCCCOC(COC)COP(O)(O)=S | 10.1016/j.bmcl.2013.01.002 | ||
| 71599962 | 89103 | None | 0 | Human | Binding | pEC50 | = | 8.4 | 8.4 | - | 0 | Agonist activity at human LPA4 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay in presence of Ki16425Agonist activity at human LPA4 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay in presence of Ki16425 |
ChEMBL | 440 | 22 | 2 | 4 | 6.1 | CCCCCCCCCCCCCCCCCOC(COC)COP(O)(O)=S | 10.1016/j.bmcl.2013.01.002 | ||
| CHEMBL2335050 | 89103 | None | 0 | Human | Binding | pEC50 | = | 8.4 | 8.4 | - | 0 | Agonist activity at human LPA4 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay in presence of Ki16425Agonist activity at human LPA4 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay in presence of Ki16425 |
ChEMBL | 440 | 22 | 2 | 4 | 6.1 | CCCCCCCCCCCCCCCCCOC(COC)COP(O)(O)=S | 10.1016/j.bmcl.2013.01.002 | ||
| CHEMBL2365071 | 89103 | None | 0 | Human | Binding | pEC50 | = | 8.4 | 8.4 | - | 0 | Agonist activity at human LPA4 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay in presence of Ki16425Agonist activity at human LPA4 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay in presence of Ki16425 |
ChEMBL | 440 | 22 | 2 | 4 | 6.1 | CCCCCCCCCCCCCCCCCOC(COC)COP(O)(O)=S | 10.1016/j.bmcl.2013.01.002 | ||
| 44368508 | 45745 | None | 0 | Human | Binding | pEC50 | = | 8.3 | 8.3 | - | 0 | Agonist activity at human LPA4 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay in presence of Ki16425Agonist activity at human LPA4 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay in presence of Ki16425 |
ChEMBL | 468 | 22 | 2 | 5 | 6.0 | CCCCCCCCCCCCCCCCCC(=O)OC[C@H](COP(O)(O)=S)OC | 10.1016/j.bmcl.2013.01.002 | ||
| CHEMBL153043 | 45745 | None | 0 | Human | Binding | pEC50 | = | 8.3 | 8.3 | - | 0 | Agonist activity at human LPA4 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay in presence of Ki16425Agonist activity at human LPA4 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay in presence of Ki16425 |
ChEMBL | 468 | 22 | 2 | 5 | 6.0 | CCCCCCCCCCCCCCCCCC(=O)OC[C@H](COP(O)(O)=S)OC | 10.1016/j.bmcl.2013.01.002 | ||
| 71719457 | 87559 | None | 0 | Human | Binding | pEC50 | = | 8.3 | 8.3 | - | 0 | Agonist activity at human LPA4 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay in presence of Ki16425Agonist activity at human LPA4 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay in presence of Ki16425 |
ChEMBL | 454 | 23 | 2 | 4 | 6.5 | CCCCCCCCCCCCCCCCCCOC[C@H](COP(O)(O)=S)OC | 10.1016/j.bmcl.2013.01.002 | ||
| CHEMBL2335048 | 87559 | None | 0 | Human | Binding | pEC50 | = | 8.3 | 8.3 | - | 0 | Agonist activity at human LPA4 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay in presence of Ki16425Agonist activity at human LPA4 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay in presence of Ki16425 |
ChEMBL | 454 | 23 | 2 | 4 | 6.5 | CCCCCCCCCCCCCCCCCCOC[C@H](COP(O)(O)=S)OC | 10.1016/j.bmcl.2013.01.002 | ||
| 44368508 | 45745 | None | 0 | Human | Binding | pEC50 | = | 8.3 | 8.3 | - | 0 | Agonist activity at human LPA4 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay in presence of Ki16425Agonist activity at human LPA4 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay in presence of Ki16425 |
ChEMBL | 468 | 22 | 2 | 5 | 6.0 | CCCCCCCCCCCCCCCCCC(=O)OC[C@H](COP(O)(O)=S)OC | 10.1016/j.bmcl.2013.01.002 | ||
| CHEMBL153043 | 45745 | None | 0 | Human | Binding | pEC50 | = | 8.3 | 8.3 | - | 0 | Agonist activity at human LPA4 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay in presence of Ki16425Agonist activity at human LPA4 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay in presence of Ki16425 |
ChEMBL | 468 | 22 | 2 | 5 | 6.0 | CCCCCCCCCCCCCCCCCC(=O)OC[C@H](COP(O)(O)=S)OC | 10.1016/j.bmcl.2013.01.002 | ||
| 71719457 | 87559 | None | 0 | Human | Binding | pEC50 | = | 8.3 | 8.3 | - | 0 | Agonist activity at human LPA4 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay in presence of Ki16425Agonist activity at human LPA4 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay in presence of Ki16425 |
ChEMBL | 454 | 23 | 2 | 4 | 6.5 | CCCCCCCCCCCCCCCCCCOC[C@H](COP(O)(O)=S)OC | 10.1016/j.bmcl.2013.01.002 | ||
| CHEMBL2335048 | 87559 | None | 0 | Human | Binding | pEC50 | = | 8.3 | 8.3 | - | 0 | Agonist activity at human LPA4 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay in presence of Ki16425Agonist activity at human LPA4 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay in presence of Ki16425 |
ChEMBL | 454 | 23 | 2 | 4 | 6.5 | CCCCCCCCCCCCCCCCCCOC[C@H](COP(O)(O)=S)OC | 10.1016/j.bmcl.2013.01.002 | ||
| 5311263 | 4157 | None | 20 | Human | Binding | pEC50 | = | 8.1 | 8.1 | - | 1 | Agonist activity at human LPA4 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay in presence of Ki16425Agonist activity at human LPA4 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay in presence of Ki16425 |
ChEMBL | 436 | 20 | 3 | 5 | 5.0 | CCCCCCCC/C=C\CCCCCCCC(=O)OC[C@@H](O)COP(=O)(O)O | 10.1016/j.bmcl.2013.01.002 | ||
| CHEMBL117021 | 4157 | None | 20 | Human | Binding | pEC50 | = | 8.1 | 8.1 | - | 1 | Agonist activity at human LPA4 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay in presence of Ki16425Agonist activity at human LPA4 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay in presence of Ki16425 |
ChEMBL | 436 | 20 | 3 | 5 | 5.0 | CCCCCCCC/C=C\CCCCCCCC(=O)OC[C@@H](O)COP(=O)(O)O | 10.1016/j.bmcl.2013.01.002 | ||
| 5311263 | 4157 | None | 20 | Human | Binding | pEC50 | = | 8.1 | 8.1 | - | 1 | Agonist activity at human LPA4 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay in presence of Ki16425Agonist activity at human LPA4 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay in presence of Ki16425 |
ChEMBL | 436 | 20 | 3 | 5 | 5.0 | CCCCCCCC/C=C\CCCCCCCC(=O)OC[C@@H](O)COP(=O)(O)O | 10.1016/j.bmcl.2013.01.002 | ||
| CHEMBL117021 | 4157 | None | 20 | Human | Binding | pEC50 | = | 8.1 | 8.1 | - | 1 | Agonist activity at human LPA4 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay in presence of Ki16425Agonist activity at human LPA4 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay in presence of Ki16425 |
ChEMBL | 436 | 20 | 3 | 5 | 5.0 | CCCCCCCC/C=C\CCCCCCCC(=O)OC[C@@H](O)COP(=O)(O)O | 10.1016/j.bmcl.2013.01.002 | ||
| 6419701 | 125870 | None | 15 | Human | Binding | pEC50 | = | 7.1 | 7.1 | - | 0 | Agonist activity at human LPA4 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay in presence of Ki16425Agonist activity at human LPA4 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay in presence of Ki16425 |
ChEMBL | 410 | 19 | 3 | 5 | 4.5 | CCCCCCCCCCCCCCCC(=O)OC[C@@H](O)COP(=O)(O)O | 10.1016/j.bmcl.2013.01.002 | ||
| CHEMBL364797 | 125870 | None | 15 | Human | Binding | pEC50 | = | 7.1 | 7.1 | - | 0 | Agonist activity at human LPA4 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay in presence of Ki16425Agonist activity at human LPA4 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay in presence of Ki16425 |
ChEMBL | 410 | 19 | 3 | 5 | 4.5 | CCCCCCCCCCCCCCCC(=O)OC[C@@H](O)COP(=O)(O)O | 10.1016/j.bmcl.2013.01.002 | ||
| 6419701 | 125870 | None | 15 | Human | Binding | pEC50 | = | 7.1 | 7.1 | - | 0 | Agonist activity at human LPA4 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay in presence of Ki16425Agonist activity at human LPA4 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay in presence of Ki16425 |
ChEMBL | 410 | 19 | 3 | 5 | 4.5 | CCCCCCCCCCCCCCCC(=O)OC[C@@H](O)COP(=O)(O)O | 10.1016/j.bmcl.2013.01.002 | ||
Showing 1 to 50 of 59 entries