Ligand source activities (1 row/activity)
Ligands (move mouse cursor over ligand name to see structure) | Receptor | Assay information | Chemical information | ||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sel. page | Common name |
GPCRdb ID |
#Vendors |
Reference ligand |
Fold selectivity |
# Tested GPCRs |
Species |
p-value (-log) |
Activity Type |
Activity Relation |
Activity Value |
AssayType |
Assay Description |
Source |
Mol weight |
Rot Bonds |
H don |
H acc |
LogP |
Smiles |
DOI |
1146 | 10634 | 56 | None | - | 1 | Mouse | 5.7 | pEC50 | = | 5.7 | Functional | ChEMBL | 59 | 0 | 0 | 1 | 0.2 | CN(C)C | 10.1039/C5MD00490J | ||
5521 | 10634 | 56 | None | - | 1 | Mouse | 5.7 | pEC50 | = | 5.7 | Functional | ChEMBL | 59 | 0 | 0 | 1 | 0.2 | CN(C)C | 10.1039/C5MD00490J | ||
CHEMBL439723 | 10634 | 56 | None | - | 1 | Mouse | 5.7 | pEC50 | = | 5.7 | Functional | ChEMBL | 59 | 0 | 0 | 1 | 0.2 | CN(C)C | 10.1039/C5MD00490J | ||
56946474 | 78291 | 0 | None | - | 1 | Mouse | 4.5 | pIC50 | = | 4.5 | Functional | ChEMBL | 403 | 9 | 1 | 4 | 4.8 | COc1ccccc1OCCNCC1CCC(c2ccccc2)(c2ccccc2)O1 | 10.1039/C5MD00490J | ||
CHEMBL1946779 | 78291 | 0 | None | - | 1 | Mouse | 4.5 | pIC50 | = | 4.5 | Functional | ChEMBL | 403 | 9 | 1 | 4 | 4.8 | COc1ccccc1OCCNCC1CCC(c2ccccc2)(c2ccccc2)O1 | 10.1039/C5MD00490J | ||
CHEMBL1962769 | 78291 | 0 | None | - | 1 | Mouse | 4.5 | pIC50 | = | 4.5 | Functional | ChEMBL | 403 | 9 | 1 | 4 | 4.8 | COc1ccccc1OCCNCC1CCC(c2ccccc2)(c2ccccc2)O1 | 10.1039/C5MD00490J | ||
56946573 | 78301 | 0 | None | - | 1 | Mouse | 5.3 | pIC50 | = | 5.3 | Functional | ChEMBL | 428 | 6 | 0 | 4 | 4.9 | COc1ccccc1N1CCN(CC2CCC(c3ccccc3)(c3ccccc3)O2)CC1 | 10.1039/C5MD00490J | ||
CHEMBL1946780 | 78301 | 0 | None | - | 1 | Mouse | 5.3 | pIC50 | = | 5.3 | Functional | ChEMBL | 428 | 6 | 0 | 4 | 4.9 | COc1ccccc1N1CCN(CC2CCC(c3ccccc3)(c3ccccc3)O2)CC1 | 10.1039/C5MD00490J | ||
CHEMBL1962870 | 78301 | 0 | None | - | 1 | Mouse | 5.3 | pIC50 | = | 5.3 | Functional | ChEMBL | 428 | 6 | 0 | 4 | 4.9 | COc1ccccc1N1CCN(CC2CCC(c3ccccc3)(c3ccccc3)O2)CC1 | 10.1039/C5MD00490J | ||
11723 | 8207 | 0 | None | - | 1 | Mouse | 6.2 | pEC50 | = | 6.2 | Functional | Guide to Pharmacology | 73 | 1 | 0 | 1 | 0.6 | CCN(C)C | 17088868 | ||
5523 | 8207 | 0 | None | - | 1 | Mouse | 6.2 | pEC50 | = | 6.2 | Functional | Guide to Pharmacology | 73 | 1 | 0 | 1 | 0.6 | CCN(C)C | 17088868 | ||
CHEMBL609099 | 8207 | 0 | None | - | 1 | Mouse | 6.2 | pEC50 | = | 6.2 | Functional | Guide to Pharmacology | 73 | 1 | 0 | 1 | 0.6 | CCN(C)C | 17088868 | ||
1146 | 10634 | 56 | None | - | 1 | Mouse | 6.5 | pEC50 | = | 6.5 | Functional | Guide to Pharmacology | 59 | 0 | 0 | 1 | 0.2 | CN(C)C | 16878137 | ||
5521 | 10634 | 56 | None | - | 1 | Mouse | 6.5 | pEC50 | = | 6.5 | Functional | Guide to Pharmacology | 59 | 0 | 0 | 1 | 0.2 | CN(C)C | 16878137 | ||
CHEMBL439723 | 10634 | 56 | None | - | 1 | Mouse | 6.5 | pEC50 | = | 6.5 | Functional | Guide to Pharmacology | 59 | 0 | 0 | 1 | 0.2 | CN(C)C | 16878137 |
Ligands (move mouse cursor over ligand name to see structure) | Receptor | Assay information | Chemical information | |||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sel. page | Similar- ity |
Common name |
GPCRdb ID |
#Vendors |
Reference ligand |
Fold selectivity |
# Tested GPCRs |
Species |
p-value (-log) |
Activity Type |
Activity Relation |
Activity Value |
Assay Type |
Assay Description |
Source |
Mol weight |
Rot Bonds |
H don |
H acc |
LogP |
Smiles |
DOI |
9950514 | 18630 | 13 | None | - | 0 | Human | 5.4 | pEC50 | = | 5.4 | Binding | ChEMBL | 355 | 4 | 2 | 3 | 3.3 | NCCc1ccc(Oc2ccc(O)cc2)c(I)c1 | 10.1039/C5MD00490J | |||
CHEMBL1182312 | 18630 | 13 | None | - | 0 | Human | 5.4 | pEC50 | = | 5.4 | Binding | ChEMBL | 355 | 4 | 2 | 3 | 3.3 | NCCc1ccc(Oc2ccc(O)cc2)c(I)c1 | 10.1039/C5MD00490J | |||
CHEMBL229288 | 18630 | 13 | None | - | 0 | Human | 5.4 | pEC50 | = | 5.4 | Binding | ChEMBL | 355 | 4 | 2 | 3 | 3.3 | NCCc1ccc(Oc2ccc(O)cc2)c(I)c1 | 10.1039/C5MD00490J |