Ligand source activities (1 row/activity)
Ligands (move mouse cursor over ligand name to see structure) | Receptor | Assay information | Chemical information | ||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sel. page | Common name |
GPCRdb ID |
#Vendors |
Reference ligand |
Fold selectivity |
# Tested GPCRs |
Species |
p-value (-log) |
Activity Type |
Activity Relation |
Activity Value |
AssayType |
Assay Description |
Source |
Mol weight |
Rot Bonds |
H don |
H acc |
LogP |
Smiles |
DOI |
1499 | 8872 | 47 | None | -63 | 38 | Human | 8.3 | pEC50 | = | 8.3 | Functional | ChEMBL | 211 | 4 | 4 | 4 | 1.1 | CC(NCC(c1ccc(c(c1)O)O)O)C | nan | ||
3779 | 8872 | 47 | None | -63 | 38 | Human | 8.3 | pEC50 | = | 8.3 | Functional | ChEMBL | 211 | 4 | 4 | 4 | 1.1 | CC(NCC(c1ccc(c(c1)O)O)O)C | nan | ||
536 | 8872 | 47 | None | -63 | 38 | Human | 8.3 | pEC50 | = | 8.3 | Functional | ChEMBL | 211 | 4 | 4 | 4 | 1.1 | CC(NCC(c1ccc(c(c1)O)O)O)C | nan | ||
CHEMBL434 | 8872 | 47 | None | -63 | 38 | Human | 8.3 | pEC50 | = | 8.3 | Functional | ChEMBL | 211 | 4 | 4 | 4 | 1.1 | CC(NCC(c1ccc(c(c1)O)O)O)C | nan | ||
DB01064 | 8872 | 47 | None | -63 | 38 | Human | 8.3 | pEC50 | = | 8.3 | Functional | ChEMBL | 211 | 4 | 4 | 4 | 1.1 | CC(NCC(c1ccc(c(c1)O)O)O)C | nan | ||
1499 | 8872 | 47 | None | -63 | 38 | Human | 8.1 | pEC50 | = | 8.1 | Functional | Drug Central | 211 | 4 | 4 | 4 | 1.1 | CC(NCC(c1ccc(c(c1)O)O)O)C | None | ||
3779 | 8872 | 47 | None | -63 | 38 | Human | 8.1 | pEC50 | = | 8.1 | Functional | Drug Central | 211 | 4 | 4 | 4 | 1.1 | CC(NCC(c1ccc(c(c1)O)O)O)C | None | ||
536 | 8872 | 47 | None | -63 | 38 | Human | 8.1 | pEC50 | = | 8.1 | Functional | Drug Central | 211 | 4 | 4 | 4 | 1.1 | CC(NCC(c1ccc(c(c1)O)O)O)C | None | ||
CHEMBL434 | 8872 | 47 | None | -63 | 38 | Human | 8.1 | pEC50 | = | 8.1 | Functional | Drug Central | 211 | 4 | 4 | 4 | 1.1 | CC(NCC(c1ccc(c(c1)O)O)O)C | None | ||
DB01064 | 8872 | 47 | None | -63 | 38 | Human | 8.1 | pEC50 | = | 8.1 | Functional | Drug Central | 211 | 4 | 4 | 4 | 1.1 | CC(NCC(c1ccc(c(c1)O)O)O)C | None | ||
2367 | 7751 | 86 | None | -1148 | 6 | Human | 3.0 | pEC50 | = | 3.0 | Functional | Guide to Pharmacology | 399 | 5 | 1 | 6 | 2.9 | COc1c(OC)cc2c(c1OC)c1ccc(c(=O)cc1[C@H](CC2)NC(=O)C)OC | 20022913 | ||
6167 | 7751 | 86 | None | -1148 | 6 | Human | 3.0 | pEC50 | = | 3.0 | Functional | Guide to Pharmacology | 399 | 5 | 1 | 6 | 2.9 | COc1c(OC)cc2c(c1OC)c1ccc(c(=O)cc1[C@H](CC2)NC(=O)C)OC | 20022913 | ||
726 | 7751 | 86 | None | -1148 | 6 | Human | 3.0 | pEC50 | = | 3.0 | Functional | Guide to Pharmacology | 399 | 5 | 1 | 6 | 2.9 | COc1c(OC)cc2c(c1OC)c1ccc(c(=O)cc1[C@H](CC2)NC(=O)C)OC | 20022913 | ||
CHEMBL107 | 7751 | 86 | None | -1148 | 6 | Human | 3.0 | pEC50 | = | 3.0 | Functional | Guide to Pharmacology | 399 | 5 | 1 | 6 | 2.9 | COc1c(OC)cc2c(c1OC)c1ccc(c(=O)cc1[C@H](CC2)NC(=O)C)OC | 20022913 | ||
DB01394 | 7751 | 86 | None | -1148 | 6 | Human | 3.0 | pEC50 | = | 3.0 | Functional | Guide to Pharmacology | 399 | 5 | 1 | 6 | 2.9 | COc1c(OC)cc2c(c1OC)c1ccc(c(=O)cc1[C@H](CC2)NC(=O)C)OC | 20022913 | ||
12423 | 10464 | 0 | None | - | 1 | Human | 3.5 | pEC50 | = | 3.5 | Functional | Guide to Pharmacology | 804 | 9 | 11 | 18 | -2.9 | C[C@@]12CCC[C@@]([C@H]1CC[C@]34[C@H]2CC[C@](C3)(C(=C)C4)O[C@H]5[C@@H]([C@H]([C@@H]([C@H](O5)CO)O)O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O)(C)C(=O)O[C@H]7[C@@H]([C@H]([C@@H]([C@H](O7)CO)O)O)O | 22616809 | ||
442089 | 10464 | 0 | None | - | 1 | Human | 3.5 | pEC50 | = | 3.5 | Functional | Guide to Pharmacology | 804 | 9 | 11 | 18 | -2.9 | C[C@@]12CCC[C@@]([C@H]1CC[C@]34[C@H]2CC[C@](C3)(C(=C)C4)O[C@H]5[C@@H]([C@H]([C@@H]([C@H](O5)CO)O)O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O)(C)C(=O)O[C@H]7[C@@H]([C@H]([C@@H]([C@H](O7)CO)O)O)O | 22616809 | ||
CHEMBL444122 | 10464 | 0 | None | - | 1 | Human | 3.5 | pEC50 | = | 3.5 | Functional | Guide to Pharmacology | 804 | 9 | 11 | 18 | -2.9 | C[C@@]12CCC[C@@]([C@H]1CC[C@]34[C@H]2CC[C@](C3)(C(=C)C4)O[C@H]5[C@@H]([C@H]([C@@H]([C@H](O5)CO)O)O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O)(C)C(=O)O[C@H]7[C@@H]([C@H]([C@@H]([C@H](O7)CO)O)O)O | 22616809 | ||
138107041 | 7349 | 65 | None | -562 | 3 | Human | 4.1 | pEC50 | = | 4.1 | Functional | Guide to Pharmacology | 749 | 7 | 5 | 14 | 1.9 | CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@@H]2O[C@@H](C)[C@@H]([C@](C2)(C)OC)O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)C[C@@H]([C@H]2O)N(C)C)[C@](C[C@H](CN([C@@H]([C@H]([C@]1(C)O)O)C)C)C)(C)O | 30011231 | ||
276 | 7349 | 65 | None | -562 | 3 | Human | 4.1 | pEC50 | = | 4.1 | Functional | Guide to Pharmacology | 749 | 7 | 5 | 14 | 1.9 | CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@@H]2O[C@@H](C)[C@@H]([C@](C2)(C)OC)O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)C[C@@H]([C@H]2O)N(C)C)[C@](C[C@H](CN([C@@H]([C@H]([C@]1(C)O)O)C)C)C)(C)O | 30011231 | ||
447043 | 7349 | 65 | None | -562 | 3 | Human | 4.1 | pEC50 | = | 4.1 | Functional | Guide to Pharmacology | 749 | 7 | 5 | 14 | 1.9 | CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@@H]2O[C@@H](C)[C@@H]([C@](C2)(C)OC)O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)C[C@@H]([C@H]2O)N(C)C)[C@](C[C@H](CN([C@@H]([C@H]([C@]1(C)O)O)C)C)C)(C)O | 30011231 | ||
6510 | 7349 | 65 | None | -562 | 3 | Human | 4.1 | pEC50 | = | 4.1 | Functional | Guide to Pharmacology | 749 | 7 | 5 | 14 | 1.9 | CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@@H]2O[C@@H](C)[C@@H]([C@](C2)(C)OC)O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)C[C@@H]([C@H]2O)N(C)C)[C@](C[C@H](CN([C@@H]([C@H]([C@]1(C)O)O)C)C)C)(C)O | 30011231 | ||
CHEMBL529 | 7349 | 65 | None | -562 | 3 | Human | 4.1 | pEC50 | = | 4.1 | Functional | Guide to Pharmacology | 749 | 7 | 5 | 14 | 1.9 | CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@@H]2O[C@@H](C)[C@@H]([C@](C2)(C)OC)O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)C[C@@H]([C@H]2O)N(C)C)[C@](C[C@H](CN([C@@H]([C@H]([C@]1(C)O)O)C)C)C)(C)O | 30011231 | ||
DB00207 | 7349 | 65 | None | -562 | 3 | Human | 4.1 | pEC50 | = | 4.1 | Functional | Guide to Pharmacology | 749 | 7 | 5 | 14 | 1.9 | CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@@H]2O[C@@H](C)[C@@H]([C@](C2)(C)OC)O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)C[C@@H]([C@H]2O)N(C)C)[C@](C[C@H](CN([C@@H]([C@H]([C@]1(C)O)O)C)C)C)(C)O | 30011231 | ||
12424 | 9151 | 0 | None | - | 1 | Human | 4.5 | pEC50 | = | 4.5 | Functional | Guide to Pharmacology | None | None | None | None | 23214402 | ||||
44398561 | 9151 | 0 | None | - | 1 | Human | 4.5 | pEC50 | = | 4.5 | Functional | Guide to Pharmacology | None | None | None | None | 23214402 | ||||
CHEMBL434535 | 9151 | 0 | None | - | 1 | Human | 4.5 | pEC50 | = | 4.5 | Functional | Guide to Pharmacology | None | None | None | None | 23214402 | ||||
10362 | 7015 | 69 | None | -1096 | 2 | Human | 4.5 | pIC50 | = | 4.5 | Functional | Guide to Pharmacology | 264 | 3 | 2 | 3 | 2.3 | OC(=O)/C=C(\C=C\C1(O)C(=CC(=O)CC1(C)C)C)/C | 25844797 | ||
5375199 | 7015 | 69 | None | -1096 | 2 | Human | 4.5 | pIC50 | = | 4.5 | Functional | Guide to Pharmacology | 264 | 3 | 2 | 3 | 2.3 | OC(=O)/C=C(\C=C\C1(O)C(=CC(=O)CC1(C)C)C)/C | 25844797 | ||
CHEMBL379808 | 7015 | 69 | None | -1096 | 2 | Human | 4.5 | pIC50 | = | 4.5 | Functional | Guide to Pharmacology | 264 | 3 | 2 | 3 | 2.3 | OC(=O)/C=C(\C=C\C1(O)C(=CC(=O)CC1(C)C)C)/C | 25844797 |
Ligands (move mouse cursor over ligand name to see structure) | Receptor | Assay information | Chemical information | |||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sel. page | Similar- ity |
Common name |
GPCRdb ID |
#Vendors |
Reference ligand |
Fold selectivity |
# Tested GPCRs |
Species |
p-value (-log) |
Activity Type |
Activity Relation |
Activity Value |
Assay Type |
Assay Description |
Source |
Mol weight |
Rot Bonds |
H don |
H acc |
LogP |
Smiles |
DOI |