Ligand source activities (1 row/activity)





Ligands (move mouse cursor over ligand name to see structure) Receptor Assay information Chemical information
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1499 8872 47 None -63 38 Human 8.3 pEC50 = 8.3 Functional
Agonist activity at human TAS2R9 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assayAgonist activity at human TAS2R9 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assay
ChEMBL 211 4 4 4 1.1 CC(NCC(c1ccc(c(c1)O)O)O)C nan
3779 8872 47 None -63 38 Human 8.3 pEC50 = 8.3 Functional
Agonist activity at human TAS2R9 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assayAgonist activity at human TAS2R9 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assay
ChEMBL 211 4 4 4 1.1 CC(NCC(c1ccc(c(c1)O)O)O)C nan
536 8872 47 None -63 38 Human 8.3 pEC50 = 8.3 Functional
Agonist activity at human TAS2R9 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assayAgonist activity at human TAS2R9 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assay
ChEMBL 211 4 4 4 1.1 CC(NCC(c1ccc(c(c1)O)O)O)C nan
CHEMBL434 8872 47 None -63 38 Human 8.3 pEC50 = 8.3 Functional
Agonist activity at human TAS2R9 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assayAgonist activity at human TAS2R9 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assay
ChEMBL 211 4 4 4 1.1 CC(NCC(c1ccc(c(c1)O)O)O)C nan
DB01064 8872 47 None -63 38 Human 8.3 pEC50 = 8.3 Functional
Agonist activity at human TAS2R9 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assayAgonist activity at human TAS2R9 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assay
ChEMBL 211 4 4 4 1.1 CC(NCC(c1ccc(c(c1)O)O)O)C nan
1499 8872 47 None -63 38 Human 8.1 pEC50 = 8.1 Functional
Agonist activity at human TAS2R9 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assayAgonist activity at human TAS2R9 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assay
Drug Central 211 4 4 4 1.1 CC(NCC(c1ccc(c(c1)O)O)O)C None
3779 8872 47 None -63 38 Human 8.1 pEC50 = 8.1 Functional
Agonist activity at human TAS2R9 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assayAgonist activity at human TAS2R9 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assay
Drug Central 211 4 4 4 1.1 CC(NCC(c1ccc(c(c1)O)O)O)C None
536 8872 47 None -63 38 Human 8.1 pEC50 = 8.1 Functional
Agonist activity at human TAS2R9 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assayAgonist activity at human TAS2R9 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assay
Drug Central 211 4 4 4 1.1 CC(NCC(c1ccc(c(c1)O)O)O)C None
CHEMBL434 8872 47 None -63 38 Human 8.1 pEC50 = 8.1 Functional
Agonist activity at human TAS2R9 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assayAgonist activity at human TAS2R9 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assay
Drug Central 211 4 4 4 1.1 CC(NCC(c1ccc(c(c1)O)O)O)C None
DB01064 8872 47 None -63 38 Human 8.1 pEC50 = 8.1 Functional
Agonist activity at human TAS2R9 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assayAgonist activity at human TAS2R9 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assay
Drug Central 211 4 4 4 1.1 CC(NCC(c1ccc(c(c1)O)O)O)C None
2270 9945 69 None -446 3 Human 2.6 pEC50 = 2.6 Functional
UnclassifiedUnclassified
Guide to Pharmacology 235 6 2 3 1.3 CCN(CCNC(=O)c1ccc(cc1)N)CC 19092995
4811 9945 69 None -446 3 Human 2.6 pEC50 = 2.6 Functional
UnclassifiedUnclassified
Guide to Pharmacology 235 6 2 3 1.3 CCN(CCNC(=O)c1ccc(cc1)N)CC 19092995
4913 9945 69 None -446 3 Human 2.6 pEC50 = 2.6 Functional
UnclassifiedUnclassified
Guide to Pharmacology 235 6 2 3 1.3 CCN(CCNC(=O)c1ccc(cc1)N)CC 19092995
CHEMBL640 9945 69 None -446 3 Human 2.6 pEC50 = 2.6 Functional
UnclassifiedUnclassified
Guide to Pharmacology 235 6 2 3 1.3 CCN(CCNC(=O)c1ccc(cc1)N)CC 19092995
DB01035 9945 69 None -446 3 Human 2.6 pEC50 = 2.6 Functional
UnclassifiedUnclassified
Guide to Pharmacology 235 6 2 3 1.3 CCN(CCNC(=O)c1ccc(cc1)N)CC 19092995
2200 9905 46 None -239883 10 Human 2.7 pEC50 = 2.7 Functional
UnclassifiedUnclassified
Guide to Pharmacology 351 2 1 5 1.6 CN1CCN(CC1)CC(=O)n1c2ccccc2c(=O)[nH]c2c1nccc2 19092995
328 9905 46 None -239883 10 Human 2.7 pEC50 = 2.7 Functional
UnclassifiedUnclassified
Guide to Pharmacology 351 2 1 5 1.6 CN1CCN(CC1)CC(=O)n1c2ccccc2c(=O)[nH]c2c1nccc2 19092995
4848 9905 46 None -239883 10 Human 2.7 pEC50 = 2.7 Functional
UnclassifiedUnclassified
Guide to Pharmacology 351 2 1 5 1.6 CN1CCN(CC1)CC(=O)n1c2ccccc2c(=O)[nH]c2c1nccc2 19092995
CHEMBL9967 9905 46 None -239883 10 Human 2.7 pEC50 = 2.7 Functional
UnclassifiedUnclassified
Guide to Pharmacology 351 2 1 5 1.6 CN1CCN(CC1)CC(=O)n1c2ccccc2c(=O)[nH]c2c1nccc2 19092995
DB00670 9905 46 None -239883 10 Human 2.7 pEC50 = 2.7 Functional
UnclassifiedUnclassified
Guide to Pharmacology 351 2 1 5 1.6 CN1CCN(CC1)CC(=O)n1c2ccccc2c(=O)[nH]c2c1nccc2 19092995
10918 9684 118 None -45708 3 Human 3.7 pEC50 = 3.7 Functional
UnclassifiedUnclassified
Guide to Pharmacology 361 2 1 6 1.5 CN1CCN(CC1)c1c(F)cc2c3c1OCC(n3cc(c2=O)C(=O)O)C 19092995
1981 9684 118 None -45708 3 Human 3.7 pEC50 = 3.7 Functional
UnclassifiedUnclassified
Guide to Pharmacology 361 2 1 6 1.5 CN1CCN(CC1)c1c(F)cc2c3c1OCC(n3cc(c2=O)C(=O)O)C 19092995
4583 9684 118 None -45708 3 Human 3.7 pEC50 = 3.7 Functional
UnclassifiedUnclassified
Guide to Pharmacology 361 2 1 6 1.5 CN1CCN(CC1)c1c(F)cc2c3c1OCC(n3cc(c2=O)C(=O)O)C 19092995
CHEMBL4 9684 118 None -45708 3 Human 3.7 pEC50 = 3.7 Functional
UnclassifiedUnclassified
Guide to Pharmacology 361 2 1 6 1.5 CN1CCN(CC1)c1c(F)cc2c3c1OCC(n3cc(c2=O)C(=O)O)C 19092995
DB01165 9684 118 None -45708 3 Human 3.7 pEC50 = 3.7 Functional
UnclassifiedUnclassified
Guide to Pharmacology 361 2 1 6 1.5 CN1CCN(CC1)c1c(F)cc2c3c1OCC(n3cc(c2=O)C(=O)O)C 19092995




Ligands (move mouse cursor over ligand name to see structure) Receptor Assay information Chemical information
Sel. page Similar-
ity
Common
name
GPCRdb
ID
#Vendors

Reference
ligand
Fold
selectivity
# Tested
GPCRs
Species

p-value
(-log)
Activity
Type
Activity
Relation
Activity
Value
Assay
Type
Assay
Description
Source

Mol
weight
Rot
Bonds
H don

H acc

LogP

Smiles

DOI