GPCRdb

Receptor	Activity	Chemical information
1499	2091	None	34	Human	Functional	pEC50	=	8.3	8.3	-63	38	Agonist activity at human TAS2R9 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assayAgonist activity at human TAS2R9 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assay	ChEMBL	211	4	4	4	1.1	CC(NCC(c1ccc(c(c1)O)O)O)C	nan
3779	2091	None	34	Human	Functional	pEC50	=	8.3	8.3	-63	38	Agonist activity at human TAS2R9 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assayAgonist activity at human TAS2R9 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assay	ChEMBL	211	4	4	4	1.1	CC(NCC(c1ccc(c(c1)O)O)O)C	nan
3779.0	2091	None	34	Human	Functional	pEC50	=	8.3	8.3	-63	38	Agonist activity at human TAS2R9 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assayAgonist activity at human TAS2R9 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assay	ChEMBL	211	4	4	4	1.1	CC(NCC(c1ccc(c(c1)O)O)O)C	nan
536	2091	None	34	Human	Functional	pEC50	=	8.3	8.3	-63	38	Agonist activity at human TAS2R9 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assayAgonist activity at human TAS2R9 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assay	ChEMBL	211	4	4	4	1.1	CC(NCC(c1ccc(c(c1)O)O)O)C	nan
CHEMBL434	2091	None	34	Human	Functional	pEC50	=	8.3	8.3	-63	38	Agonist activity at human TAS2R9 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assayAgonist activity at human TAS2R9 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assay	ChEMBL	211	4	4	4	1.1	CC(NCC(c1ccc(c(c1)O)O)O)C	nan
DB01064	2091	None	34	Human	Functional	pEC50	=	8.3	8.3	-63	38	Agonist activity at human TAS2R9 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assayAgonist activity at human TAS2R9 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assay	ChEMBL	211	4	4	4	1.1	CC(NCC(c1ccc(c(c1)O)O)O)C	nan
1499	2091	None	34	Human	Functional	pEC50	=	8.1	8.1	-63	38	Agonist activity at human TAS2R9 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assayAgonist activity at human TAS2R9 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assay	Drug Central	211	4	4	4	1.1	CC(NCC(c1ccc(c(c1)O)O)O)C	None
3779	2091	None	34	Human	Functional	pEC50	=	8.1	8.1	-63	38	Agonist activity at human TAS2R9 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assayAgonist activity at human TAS2R9 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assay	Drug Central	211	4	4	4	1.1	CC(NCC(c1ccc(c(c1)O)O)O)C	None
3779.0	2091	None	34	Human	Functional	pEC50	=	8.1	8.1	-63	38	Agonist activity at human TAS2R9 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assayAgonist activity at human TAS2R9 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assay	Drug Central	211	4	4	4	1.1	CC(NCC(c1ccc(c(c1)O)O)O)C	None
536	2091	None	34	Human	Functional	pEC50	=	8.1	8.1	-63	38	Agonist activity at human TAS2R9 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assayAgonist activity at human TAS2R9 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assay	Drug Central	211	4	4	4	1.1	CC(NCC(c1ccc(c(c1)O)O)O)C	None
CHEMBL434	2091	None	34	Human	Functional	pEC50	=	8.1	8.1	-63	38	Agonist activity at human TAS2R9 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assayAgonist activity at human TAS2R9 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assay	Drug Central	211	4	4	4	1.1	CC(NCC(c1ccc(c(c1)O)O)O)C	None
DB01064	2091	None	34	Human	Functional	pEC50	=	8.1	8.1	-63	38	Agonist activity at human TAS2R9 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assayAgonist activity at human TAS2R9 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assay	Drug Central	211	4	4	4	1.1	CC(NCC(c1ccc(c(c1)O)O)O)C	None
2270	3171	None	45	Human	Functional	pEC50	=	2.6	2.6	-446	3	UnclassifiedUnclassified	Guide to Pharmacology	235	6	2	3	1.3	CCN(CCNC(=O)c1ccc(cc1)N)CC	19092995
4811	3171	None	45	Human	Functional	pEC50	=	2.6	2.6	-446	3	UnclassifiedUnclassified	Guide to Pharmacology	235	6	2	3	1.3	CCN(CCNC(=O)c1ccc(cc1)N)CC	19092995
4913	3171	None	45	Human	Functional	pEC50	=	2.6	2.6	-446	3	UnclassifiedUnclassified	Guide to Pharmacology	235	6	2	3	1.3	CCN(CCNC(=O)c1ccc(cc1)N)CC	19092995
CHEMBL640	3171	None	45	Human	Functional	pEC50	=	2.6	2.6	-446	3	UnclassifiedUnclassified	Guide to Pharmacology	235	6	2	3	1.3	CCN(CCNC(=O)c1ccc(cc1)N)CC	19092995
DB01035	3171	None	45	Human	Functional	pEC50	=	2.6	2.6	-446	3	UnclassifiedUnclassified	Guide to Pharmacology	235	6	2	3	1.3	CCN(CCNC(=O)c1ccc(cc1)N)CC	19092995
2200	3131	None	31	Human	Functional	pEC50	=	2.7	2.7	-239883	10	UnclassifiedUnclassified	Guide to Pharmacology	351	2	1	5	1.6	CN1CCN(CC1)CC(=O)n1c2ccccc2c(=O)[nH]c2c1nccc2	19092995
328	3131	None	31	Human	Functional	pEC50	=	2.7	2.7	-239883	10	UnclassifiedUnclassified	Guide to Pharmacology	351	2	1	5	1.6	CN1CCN(CC1)CC(=O)n1c2ccccc2c(=O)[nH]c2c1nccc2	19092995
4848	3131	None	31	Human	Functional	pEC50	=	2.7	2.7	-239883	10	UnclassifiedUnclassified	Guide to Pharmacology	351	2	1	5	1.6	CN1CCN(CC1)CC(=O)n1c2ccccc2c(=O)[nH]c2c1nccc2	19092995
4848.0	3131	None	31	Human	Functional	pEC50	=	2.7	2.7	-239883	10	UnclassifiedUnclassified	Guide to Pharmacology	351	2	1	5	1.6	CN1CCN(CC1)CC(=O)n1c2ccccc2c(=O)[nH]c2c1nccc2	19092995
CHEMBL9967	3131	None	31	Human	Functional	pEC50	=	2.7	2.7	-239883	10	UnclassifiedUnclassified	Guide to Pharmacology	351	2	1	5	1.6	CN1CCN(CC1)CC(=O)n1c2ccccc2c(=O)[nH]c2c1nccc2	19092995
DB00670	3131	None	31	Human	Functional	pEC50	=	2.7	2.7	-239883	10	UnclassifiedUnclassified	Guide to Pharmacology	351	2	1	5	1.6	CN1CCN(CC1)CC(=O)n1c2ccccc2c(=O)[nH]c2c1nccc2	19092995
10918	2909	None	72	Human	Functional	pEC50	=	3.7	3.7	-45708	3	UnclassifiedUnclassified	Guide to Pharmacology	361	2	1	6	1.5	CN1CCN(CC1)c1c(F)cc2c3c1OCC(n3cc(c2=O)C(=O)O)C	19092995
1981	2909	None	72	Human	Functional	pEC50	=	3.7	3.7	-45708	3	UnclassifiedUnclassified	Guide to Pharmacology	361	2	1	6	1.5	CN1CCN(CC1)c1c(F)cc2c3c1OCC(n3cc(c2=O)C(=O)O)C	19092995
4583	2909	None	72	Human	Functional	pEC50	=	3.7	3.7	-45708	3	UnclassifiedUnclassified	Guide to Pharmacology	361	2	1	6	1.5	CN1CCN(CC1)c1c(F)cc2c3c1OCC(n3cc(c2=O)C(=O)O)C	19092995
CHEMBL4	2909	None	72	Human	Functional	pEC50	=	3.7	3.7	-45708	3	UnclassifiedUnclassified	Guide to Pharmacology	361	2	1	6	1.5	CN1CCN(CC1)c1c(F)cc2c3c1OCC(n3cc(c2=O)C(=O)O)C	19092995
DB01165	2909	None	72	Human	Functional	pEC50	=	3.7	3.7	-45708	3	UnclassifiedUnclassified	Guide to Pharmacology	361	2	1	6	1.5	CN1CCN(CC1)c1c(F)cc2c3c1OCC(n3cc(c2=O)C(=O)O)C	19092995

Ligands (move mouse cursor over ligand name to see structure)					Receptor		Activity									Chemical information
Sel. page	Common name No matches found	GPCRdb ID No matches found	Reference ligand No matches found	Vendors	Species No matches found		Assay Type No matches found	Activity Type No matches found	Activity Relation No matches found	Activity Value	p-value (-log)	Fold selectivity	Tested GPCRs	Assay Description No matches found	Source No matches found	Mol weight	Rot Bonds	H don	H acc	LogP	Smiles No matches found	DOI No matches found

Ligands (move mouse cursor over ligand name to see structure)					Receptor		Activity									Chemical information
Sel. page	Common name No matches found	GPCRdb ID No matches found	Reference ligand No matches found	Vendors	Species No matches found		Assay Type No matches found	Activity Type No matches found	Activity Relation No matches found	Activity Value	p-value (-log)	Fold selectivity	Tested GPCRs	Assay Description No matches found	Source No matches found	Mol weight	Rot Bonds	H don	H acc	LogP	Smiles No matches found	DOI No matches found
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Main reference

Ligand source activities (1 row/activity)